B3GAT3 and SEC22B

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		B3GAT3	SEC22B
Description		beta-1,3-glucuronyltransferase 3	SEC22 homolog B, vesicle trafficking protein (gene/pseudogene)
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GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Cis-Golgi Network Membrane Integral Component Of Membrane Extracellular Exosome	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Synaptic Vesicle ER To Golgi Transport Vesicle Membrane Integral Component Of Membrane Transport Vesicle COPI-coated Vesicle Phagocytic Vesicle Membrane SNARE Complex Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Melanosome
	Molecular Function	Protein Binding Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase Activity Glucuronosyltransferase Activity Metal Ion Binding Protein Phosphatase Activator Activity	SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Carbohydrate Metabolic Process Glycosaminoglycan Biosynthetic Process Protein Glycosylation Heparan Sulfate Proteoglycan Biosynthetic Process Glycosaminoglycan Metabolic Process Positive Regulation Of Catalytic Activity Regulation Of Phosphoprotein Phosphatase Activity Chondroitin Sulfate Proteoglycan Biosynthetic Process Dermatan Sulfate Proteoglycan Biosynthetic Process Positive Regulation Of Intracellular Protein Transport	Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent ER To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To ER Protein Transport Positive Regulation Of Protein Catabolic Process COPII Vesicle Coating Vesicle Fusion With Golgi Apparatus Negative Regulation Of Autophagosome Assembly Vesicle Fusion With Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Membrane
Pathways		A tetrasaccharide linker sequence is required for GAG synthesis Defective B3GAT3 causes JDSSDHD	ER-Phagosome pathway COPII-mediated vesicle transport Cargo concentration in the ER COPI-dependent Golgi-to-ER retrograde traffic
Drugs		UDP-alpha-D-glucuronic acid Uridine-5'-Diphosphate
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Iris color (L* coordinate) ( 30895295)
Interacting Genes		2 interacting genes: HNRNPD SEC22B	5 interacting genes: B3GAT3 CREB3 LMNA STX1A STX5
Entrez ID		26229	9554
HPRD ID		07564	04939
Ensembl ID		ENSG00000149541	ENSG00000265808
Uniprot IDs		G3V150 O94766 Q5U676	O75396
PDB IDs		1FGG 1KWS 3CU0	2NUP 2NUT 3EGD 3EGX
Enriched GO Terms of Interacting Partners?
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