PRPF31 and ZNF24

Number of citations of the paper that reports this interaction (PubMedID 25910212)
127

Data Source:
BioGRID (two hybrid)

		PRPF31	ZNF24
Description		pre-mRNA processing factor 31	zinc finger protein 24
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm U2-type Spliceosomal Complex U4 SnRNP U4atac SnRNP Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Precatalytic Spliceosome MLL1 Complex Spliceosomal Tri-snRNP Complex	Nucleus Nucleoplasm
	Molecular Function	RNA Binding Protein Binding U4 SnRNA Binding U4atac SnRNA Binding Ribonucleoprotein Complex Binding SnRNP Binding	DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Zinc Ion Binding Identical Protein Binding Sequence-specific DNA Binding
	Biological Process	Spliceosomal Tri-snRNP Complex Assembly MRNA Splicing, Via Spliceosome SnoRNA Localization Ribonucleoprotein Complex Localization	Myelination Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases		Retinitis pigmentosa (RP)
GWAS		Change in HbA1c levels in response to metformin treatment in type 2 diabetes ( 29650774)
Interacting Genes		76 interacting genes: C1QTNF1 CALCOCO2 CBY2 CCDC136 CCDC33 CCDC57 CCNDBP1 CDCA7L CEP70 DVL2 EFEMP2 FANCA FANCC FASTK GOLGA2 HNRNPH2 HNRNPK JAKMIP2 KCTD6 KHDRBS2 KHDRBS3 KRT15 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-8 KRTAP10-9 LDOC1 LURAP1 LZTS2 MDFI MEOX2 MID2 MIPOL1 MKRN3 MTUS2 NCAPH2 NDUFB9 NOTCH2NLA PAK5 PDE4DIP PHC2 PHF5A PNMA1 PNMA2 PPIH PRICKLE1 PRPF3 PSTPIP1 RACK1 RBM25 RBM4 RBMX RBMY1A1 RBMY1F RINT1 SIAH1 SNRNP200 SSX2IP STX11 TADA2A TFIP11 TLE5 TMCC2 TP53BP2 TRIM27 TRIM41 TSGA10 USP15 ZFP64 ZNF24 ZNF250 ZNF408 ZNF417 ZNF473 ZNF587	39 interacting genes: APLP1 CCDC130 CEP126 COPS6 CRMP1 DDX6 DZIP3 EEF1A1 EEF1G ERG28 FANCA HAP1 HMGB1 KAT5 LMO2 LRIF1 MID2 MZF1 PPP1CC PRPF31 RBM48 SCAND1 SEC62 SETDB1 TCAF1 TP53 TRIM25 TRIM41 UBE2I UNC119 UTP14A ZBTB16 ZKSCAN8 ZNF165 ZNF174 ZNF446 ZNHIT3 ZSCAN21 ZSCAN32
Entrez ID		26121	7572
HPRD ID		05917	01921
Ensembl ID		ENSG00000105618	ENSG00000172466
Uniprot IDs		Q8WWY3	P17028
PDB IDs		2OZB 3JCR 3SIU 3SIV 5O9Z 6AH0 6AHD 6QW6 6QX9	1X6E 3LHR
Enriched GO Terms of Interacting Partners?
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