SETBP1 and PLEKHF2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		SETBP1	PLEKHF2
Description		SET binding protein 1	pleckstrin homology and FYVE domain containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Nuclear Body	Endoplasmic Reticulum Transport Vesicle Early Endosome Membrane
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding	Protein Binding Phosphatidylinositol Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Protein Transport
Pathways
Drugs
Diseases		Schinzel-Giedion midface retraction syndrome
GWAS		Bone ultrasound measurement (velocity of sound) ( 28472463) Breast cancer ( 25751625 29059683 31757997) Coronary artery aneurysm in Kawasaki disease ( 27171184) Diastolic blood pressure ( 27618452) Estimated glomerular filtration rate ( 31152163) Hair color ( 26926045) Heel bone mineral density ( 30598549) Male-pattern baldness ( 29146897 22693459 28196072) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444 31624269) Number of sexual partners ( 30643258) Platelet thrombus formation ( 22550155) Pulse pressure ( 27841878) QRS duration ( 30679814 27577874 30012220 25035420 27659466) QRS interval (sulfonylurea treatment interaction) ( 27958378) Restless legs syndrome ( 29029846) Systolic blood pressure ( 27841878 28739976 27618452) Waist circumference ( 28552196)	Radiation response ( 20923822)
Interacting Genes		12 interacting genes: APP DENND11 LRRC37A11P PLEKHF2 SET SPANXA1 SPANXC SPANXD SUMO1P1 UBE2I XAGE1B YAF2	71 interacting genes: ACY3 AIDA AIMP2 APP APPL1 ARL14EP BEND7 BLOC1S6 BSCL2 CAVIN2 CCDC172 CCDC85B CEP44 CGGBP1 CHIC2 DPPA4 DRAP1 DTX2 DUT ESRP1 FBXO28 FHL3 FOXA1 FRMD8 GFER GLUL GNMT GPBP1 GPBP1L1 HEY1 HSPB7 L3MBTL3 LDOC1 MAX MBIP MEAF6 NKG7 NONO NPM2 PDP1 PEX2 PRDM14 PRKAR1A PRPSAP1 RAB39A RABAC1 RADX RSPO2 RTN1 RTN3 RTN4 S100A1 S100A13 SEPTIN2 SEPTIN5 SEPTIN6 SETBP1 SFN SPEF1 TBX3 TCN2 TNFAIP8 TRAF6 TRAPPC3 TSC22D3 TXNL4B UBE2Z USF1 ZNF250 ZNF263 ZNF398
Entrez ID		26040	79666
HPRD ID		10224	15147
Ensembl ID		ENSG00000152217	ENSG00000175895
Uniprot IDs		Q9Y6X0	Q9H8W4
PDB IDs
Enriched GO Terms of Interacting Partners?
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