LRIG1 and CBL

  • Number of citations of the paper that reports this interaction (PubMedID 15282549)
  • 97

LRIG1

CBL

Description leucine rich repeats and immunoglobulin like domains 1 Cbl proto-oncogene
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs) ( 23648065)
  • Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin) ( 23648065)
  • Antibody status in Tripanosoma cruzi seropositivity ( 24324551)
  • Atrial fibrillation ( 30061737 29892015)
  • Birth weight ( 31043758)
  • Blood urea nitrogen levels ( 29403010)
  • Carotid intima media thickness ( 21909108)
  • Chronic kidney disease ( 29124443)
  • Colorectal cancer ( 26151821)
  • Colorectal cancer or advanced adenoma ( 30510241)
  • Creatinine levels ( 29124443)
  • Estimated glomerular filtration rate ( 29124443)
  • Hyperuricemia ( 29124443)
  • Intraocular pressure ( 30054594)
  • Mean corpuscular hemoglobin ( 27863252)
  • Mean corpuscular volume ( 27863252)
  • Non-glioblastoma glioma ( 28346443)
  • Pulse pressure ( 27841878)
  • QRS duration ( 27577874 21076409 27659466)
  • Renal function-related traits (BUN) ( 22797727)
  • Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 3 peripheral neuropathy) ( 24554482)
  • Serum uric acid levels ( 29124443)
  • Systolic blood pressure ( 27841878)
  • Type 2 diabetes ( 25760438)
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes 3 interacting genes: CBL GLRX3 ZBTB16 130 interacting genes: ABL1 APPL1 ASAP1 AXL BCR BLK BLNK BTK CAPN1 CBLIF CD19 CD2AP CD38 CD40 CD5 CDKL2 CRK CRKL CSF1R CTNNB1 CUBN EGFR EIF5B EPHA2 EPHB6 EPOR EPS8 F2RL1 FGR FLOT1 FLT3 FNBP1 FRS2 FYB1 FYN GRAP2 GRB2 HCK IGF1R INPPL1 INSR ITCH ITK ITSN2 JAK2 KDR KHDRBS1 KIT KRT18 LAT LAT2 LCK LCP2 LRIG1 LTK LYN MAPK8 MET MYH9 MYO1C MZF1 NCK1 NECTIN1 NOTCH1 OSTF1 PDGFRA PDGFRB PIK3R1 PIK3R2 PLCG1 PRKCA PRKCQ PTK2B PTPN11 PTPN22 PTPN6 RET SCN5A SERPINA5 SH2B2 SH3KBP1 SHC1 SLA SLA2 SMAD7 SORBS1 SORBS2 SP7 SPRY2 SRC STAP2 STAT3 STAT5A STAT5B SYK TCN1 TCN2 TGFBR2 TGM2 TNFRSF11A TNS4 TRAF4 TRAF6 TRIM8 TYK2 UBASH3A UBASH3B UBC UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2E3 UBE2G1 UBE2G2 UBE2L3 UBE2M UBE2N UBE2U UBE2W USP21 VAV1 VAV2 YES1 YWHAB YWHAG YWHAQ YWHAZ ZAP70
Entrez ID 26018 867
HPRD ID 10057 01320
Ensembl ID ENSG00000144749 ENSG00000110395
Uniprot IDs Q96JA1 P22681
PDB IDs 4U7L 4U7M 1B47 1FBV 1YVH 2CBL 2JUJ 2K4D 2OO9 2Y1M 2Y1N 3BUM 3BUN 3BUO 3BUW 3BUX 3OB1 3OB2 3PLF 4A49 4A4B 4A4C 4GPL 5HKW 5HKX 5HKY 5HKZ 5HL0 5J3X 5O76
Enriched GO Terms of Interacting Partners?
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