GALNT3 and APPBP2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		GALNT3	APPBP2
Description		polypeptide N-acetylgalactosaminyltransferase 3	amyloid beta precursor protein binding protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Membrane Integral Component Of Membrane Golgi Cisterna Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome	Nucleus Cytoplasm Microtubule Microtubule Associated Complex Cytoplasmic Vesicle Membrane
	Molecular Function	Polypeptide N-acetylgalactosaminyltransferase Activity Calcium Ion Binding Manganese Ion Binding Carbohydrate Binding	Microtubule Motor Activity Protein Binding
	Biological Process	Carbohydrate Metabolic Process Fibroblast Growth Factor Receptor Signaling Pathway O-glycan Processing Protein O-linked Glycosylation Via Serine Protein O-linked Glycosylation Via Threonine	Intracellular Protein Transport Intracellular Transport
Pathways		FGFR3c ligand binding and activation Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) O-linked glycosylation of mucins
Drugs
Diseases
GWAS		Bone mineral density ( 21533022) Bone mineral density (paediatric, lower limb) ( 24945404) Bone mineral density (paediatric, total body less head) ( 24945404) Bone mineral density (paediatric, upper limb) ( 24945404) Lumbar spine bone mineral density ( 22504420) Spontaneous preterm birth with premature rupture of membranes ( 31194736)	Waist-hip ratio ( 28552196)
Interacting Genes		2 interacting genes: APPBP2 MAPK8IP2	81 interacting genes: - AHCY AIM2 AK3 ANKRD10 APP AR ARMCX5 C1orf50 C6orf226 CALM3 CCDC85C CCNL1 CDK16 CHMP5 CIBAR1 CLCN1 CNTFR COL24A1 CORO2B CREB3 CSNK1G2 CTC1 CYBA DCD DHRS2 DPEP1 EID3 ERO1A FAM107A FSTL1 FXYD7 GALNT3 GCSAM GP9 GSTP1 H2AC15 HIPK4 HSPA4 KIF6 KLF11 KLHL35 LANCL2 LONRF3 LUC7L2 LUZP4 MFSD3 MLLT3 MUL1 NFYA NPRL3 PCSK5 PI4KAP2 PPP1R8 PRKAA2 PRKACB PYROXD2 RASSF5 RNF128 RNF34 RRS1 SELENOI SELENOV SLC22A6 SLC25A23 SNX5 ST8SIA5 SYNRG SYT11 TAF11 TAFA4 TBL3 TCF25 UBE2R2 UGGT2 WAS WDR24 WNT5B ZC3H10 ZCCHC12 ZNF747
Entrez ID		2591	10513
HPRD ID		03453	05616
Ensembl ID		ENSG00000115339	ENSG00000062725
Uniprot IDs		Q14435	A0A024QZ47 Q92624
PDB IDs
Enriched GO Terms of Interacting Partners?
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