BRMS1 and BEX2

Number of citations of the paper that reports this interaction (PubMedID 25640309)
5

Data Source:
BioGRID (two hybrid)

		BRMS1	BEX2
Description		BRMS1 transcriptional repressor and anoikis regulator	brain expressed X-linked 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Sin3-type Complex	Nucleus Cytoplasm
	Molecular Function	Histone Deacetylase Activity Protein Binding Histone Deacetylase Binding NF-kappaB Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Apoptotic Process Histone Deacetylation Negative Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Protein Deacetylation Positive Regulation Of Anoikis	Apoptotic Process Cell Cycle Regulation Of Apoptotic Process Regulation Of Cell Cycle
Pathways		HDACs deacetylate histones
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972 31043756)
Interacting Genes		48 interacting genes: ANGPTL4 APP ARID4A BEX2 BRMS1L CEP70 CSNK2A1 CYTOR DIRAS3 DNAJB1 DNAJB6 E2F1 EEF1A1 EP300 GOLGB1 HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HSP90AA1 HSPA4 IL13RA2 ING1 KLK9 KPNA5 LRIF1 LYPD3 MRC2 NMI PFDN5 PSMC3IP RBBP4 RBBP7 RBP1 RELA SAP30 SIN3A SMARCE1 SMTN SNAI1 SNX6 SPOP SUDS3 TAF1 THRSP UBE2D1	35 interacting genes: AURKA BCAR3 BLZF1 BRMS1 CALCOCO2 CCDC85B CEP70 FGFR2 FSD2 KRT15 KRT31 KRT38 KRT40 KRTAP10-8 KRTAP4-12 KRTAP5-9 LMO2 LZTS2 MAGEA11 MAGEA4 MIPOL1 MKRN3 NECAB2 OMP PIK3CA PNMA1 PPM1D PRDM14 PTPN11 SSX2IP TRAF1 TRAF2 TRIM27 TRIM42 ZDHHC17
Entrez ID		25855	84707
HPRD ID		05879	06484
Ensembl ID		ENSG00000174744	ENSG00000133134
Uniprot IDs		G5E9I4 Q9HCU9	Q9BXY8
PDB IDs		2XUS 4AUV
Enriched GO Terms of Interacting Partners?
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