FKBP8 and ATP13A2

Number of citations of the paper that reports this interaction (PubMedID 22645275)
27

Data Source:
BioGRID (two hybrid)

		FKBP8	ATP13A2
Description		FKBP prolyl isomerase 8	ATPase cation transporting 13A2
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Endoplasmic Reticulum Cytosol Membrane Integral Component Of Endoplasmic Reticulum Membrane Mitochondrial Membrane Protein-containing Complex	Cell Lysosome Lysosomal Membrane Late Endosome Multivesicular Body Autophagosome Vesicle Membrane Integral Component Of Membrane Transport Vesicle Vesicle Multivesicular Body Membrane Neuron Projection Neuronal Cell Body Lysosomal Lumen Integral Component Of Lysosomal Membrane
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Identical Protein Binding Protein Binding Involved In Protein Folding Metal Ion Binding Disordered Domain Specific Binding	Protein Binding ATP Binding Zinc Ion Binding ATPase Activity Cation-transporting ATPase Activity Manganese Ion Binding Phosphatidic Acid Binding Phosphatidylinositol-3,5-bisphosphate Binding Cupric Ion Binding
	Biological Process	Protein Peptidyl-prolyl Isomerization Cell Fate Specification Negative Regulation Of Protein Phosphorylation Protein Folding Apoptotic Process Smoothened Signaling Pathway Viral Process Dorsal/ventral Neural Tube Patterning Positive Regulation Of BMP Signaling Pathway Multicellular Organism Growth Intracellular Signal Transduction Camera-type Eye Development Negative Regulation Of Apoptotic Process	Cellular Calcium Ion Homeostasis Cellular Iron Ion Homeostasis Cellular Zinc Ion Homeostasis Autophagy Positive Regulation Of Gene Expression Regulation Of Mitochondrion Organization Regulation Of Macroautophagy Regulation Of Autophagosome Size Cellular Cation Homeostasis Regulation Of Intracellular Protein Transport Ion Transmembrane Transport Cellular Response To Oxidative Stress Protein Autophosphorylation Positive Regulation Of Protein Secretion Regulation Of Endopeptidase Activity Zinc Ion Homeostasis Cellular Response To Manganese Ion Cellular Response To Zinc Ion Extracellular Exosome Biogenesis Cation Transmembrane Transport Regulation Of Protein Localization To Nucleus Negative Regulation Of Neuron Death Polyamine Transmembrane Transport Regulation Of Autophagy Of Mitochondrion Positive Regulation Of Exosomal Secretion Regulation Of Chaperone-mediated Autophagy Autophagosome Organization Regulation Of Glucosylceramidase Activity Regulation Of Lysosomal Protein Catabolic Process Negative Regulation Of Lysosomal Protein Catabolic Process Peptidyl-aspartic Acid Autophosphorylation Regulation Of Ubiquitin-specific Protease Activity
Pathways		Ub-specific processing proteases	Ion transport by P-type ATPases
Drugs
Diseases			Parkinson's disease (PD)
GWAS		Plasma parathyroid hormone levels ( 30134803) Urinary potassium excretion ( 31409800)	Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Height ( 25429064 31562340 20189936) Hip circumference adjusted for BMI ( 28552196 25673412) Intraocular pressure ( 29617998) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		17 interacting genes: ANKMY2 ARHGEF5 ATP13A2 BCL2 BCL2L1 BNIPL CLCN1 EGFR EGLN1 MAPK14 MTOR PPP3CA PSMC1 PSMD2 RHEB TERF1 VHL	36 interacting genes: ACKR3 ATP5MC2 CCKBR CMTM6 COL1A1 CXCR4 CYGB DCAF7 EMC7 F2R FAM111B FAM8A1 FKBP8 FUNDC2 GPR21 HIPK1 ICAM2 LMAN2 LRP6 MEX3B MYCBP2 NPY1R NRXN1 OCA2 OSTC PCDHB10 PCMTD2 PDIA6 PSME3IP1 SEC61B SPCS2 TSPAN14 UBE2J2 VAMP2 WDR5B WDR83OS
Entrez ID		23770	23400
HPRD ID		05327	13677
Ensembl ID		ENSG00000105701	ENSG00000159363
Uniprot IDs		A0A024R7P2 B2R8G6 Q14318	Q8N4D4 Q8NBS1 Q9NQ11
PDB IDs		2AWG 2D9F 2F2D 2MF9 3EY6 5MGX
Enriched GO Terms of Interacting Partners?
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