ARFIP2 and ING5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ARFIP2	ING5
Description		ADP ribosylation factor interacting protein 2	inhibitor of growth family member 5
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GO Annotations	Cellular Component	Ruffle Cytoplasm Cytosol Plasma Membrane Cell Cortex Trans-Golgi Network Membrane	Nucleus Nucleoplasm MOZ/MORF Histone Acetyltransferase Complex
	Molecular Function	Protein Binding GTP Binding Phospholipid Binding Protein Domain Specific Binding GTP-dependent Protein Binding Identical Protein Binding Cadherin Binding Rac GTPase Binding Phosphatidylinositol-4-phosphate Binding Membrane Curvature Sensor Activity	Chromatin Binding Protein Binding Methylated Histone Binding Metal Ion Binding
	Biological Process	Intracellular Protein Transport Autophagy Small GTPase Mediated Signal Transduction Lamellipodium Assembly Actin Cytoskeleton Organization Ruffle Organization Regulation Of Arp2/3 Complex-mediated Actin Nucleation	DNA Replication Protein Acetylation Negative Regulation Of Cell Proliferation Positive Regulation Of Apoptotic Process Histone H3 Acetylation Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Growth Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of Apoptotic Signaling Pathway
Pathways		Retrograde transport at the Trans-Golgi-Network	HATs acetylate histones Regulation of TP53 Activity through Acetylation
Drugs
Diseases
GWAS			Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433)
Interacting Genes		26 interacting genes: AGTRAP AKT1 APP ARF1 ARF3 ARF5 ARF6 ARL1 CDKN2A CEP63 DTNBP1 HAUS1 HGS ING5 ITGB3BP ITSN1 KRT15 LY6D MAL2 RAC1 RAC2 SNX1 SOCS2 STAT3 TRIM54 USHBP1	35 interacting genes: APC APLP1 ARFIP2 BARD1 C3orf62 CCDC33 CDCA7L CDK2 CDKN1A CEP126 CEP44 DEUP1 EP300 FAM118B GCSH HAP1 HGS HTT ICA1 IKZF3 JADE2 KRT40 KRTAP10-7 KXD1 MBIP MCM6 MEST NAV2 PCM1 PRMT5 SMARCE1 TADA3 TAF1D TP53 VIM
Entrez ID		23647	84289
HPRD ID		07209	16348
Ensembl ID		ENSG00000132254	ENSG00000168395
Uniprot IDs		A0A087X1E4 B4DUZ3 B4DXH2 P53365	A0A1B0GW41 Q8WYH8
PDB IDs		1I49 1I4D 1I4L 1I4T 4DCN	3C6W 5ME8 5MTO
Enriched GO Terms of Interacting Partners?
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