ZMYND8 and CSNK1E

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		ZMYND8	CSNK1E
Description		zinc finger MYND-type containing 8	casein kinase 1 epsilon
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Dendritic Spine Dendritic Shaft	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Transcription Corepressor Activity Protein Binding Zinc Ion Binding Protein Domain Specific Binding Methylated Histone Binding Protein N-terminus Binding Repressing Transcription Factor Binding Lysine-acetylated Histone Binding	RNA Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding
	Biological Process	Regulation Of Transcription, DNA-templated Negative Regulation Of Cell Migration Positive Regulation Of Filopodium Assembly Positive Regulation Of Dendritic Spine Development Modulation Of Excitatory Postsynaptic Potential Regulation Of Postsynaptic Density Protein 95 Clustering Positive Regulation Of Dendritic Spine Maintenance Negative Regulation Of Nucleic Acid-templated Transcription	G2/M Transition Of Mitotic Cell Cycle DNA Repair Protein Phosphorylation Signal Transduction Regulation Of G2/M Transition Of Mitotic Cell Cycle Wnt Signaling Pathway Peptidyl-serine Phosphorylation Negative Regulation Of Protein Binding Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Circadian Regulation Of Gene Expression Regulation Of Circadian Rhythm Canonical Wnt Signaling Pathway Ciliary Basal Body-plasma Membrane Docking Regulation Of Cellular Protein Localization Positive Regulation Of Wnt-mediated Midbrain Dopaminergic Neuron Differentiation Positive Regulation Of Non-canonical Wnt Signaling Pathway
Pathways			WNT mediated activation of DVL Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Circadian Clock Anchoring of the basal body to the plasma membrane Major pathway of rRNA processing in the nucleolus and cytosol AURKA Activation by TPX2
Drugs
Diseases
GWAS		Mean platelet volume ( 27863252) Metabolite levels ( 23823483) Migraine ( 27182965) Parahippocampal gyrus volume ( 31530798) Response to protease inhibitor treatment in hepatitis c (bilirubin toxicity) ( 24503447) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Keratoconus ( 31855235)
Interacting Genes		12 interacting genes: ATN1 CSNK1E FHOD1 H3C1 H4C1 PBXIP1 PRKCB RERE SPOP USP7 ZBTB7A ZFYVE9	53 interacting genes: AKAP9 ANKRD6 APC APP ARHGEF1 ARNTL AXIN1 AXIN2 BBS10 BHLHE41 BID CADM4 CLOCK CRY1 CSNK2B DELEC1 DVL1 DVL2 DVL3 ENTR1 FAM110A FAM110C FAM83D FBP1 FBXO7 FBXW11 GTF3C1 HES1 KAT7 MCC NCOA3 NR1D2 PER1 PER2 PER3 PPP1CA PPP1CC PPP1R14A PPP2R5D PPP2R5E PTPRD RAD54B RBX1 RORA RORC SOCS3 TAOK1 TAZ TNS2 TRAF3 WDCP ZMYND8 ZNF227
Entrez ID		23613	1454
HPRD ID		10166	02919
Ensembl ID		ENSG00000101040	ENSG00000213923
Uniprot IDs		A0A087WVZ6 A6H8Y8 Q2HXV5 Q569J9 Q9ULU4	P49674 Q5U045
PDB IDs		4COS 5B73 5MQ4 5Y1Z	4HNI 4HOK
Enriched GO Terms of Interacting Partners?
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