CD2AP and SOS1

  • Number of citations of the paper that reports this interaction (PubMedID 14679214)
  • 67
  • Data Source:
  • HPRD (in vitro)

CD2AP

SOS1

Description CD2 associated protein SOS Ras/Rac guanine nucleotide exchange factor 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease ( 31473137)
  • Alzheimer's disease (late onset) ( 21460841 30617256 24162737)
  • Alzheimer's disease or family history of Alzheimer's disease ( 30617256)
  • Amyotrophic lateral sclerosis (sporadic) ( 24529757)
  • Family history of Alzheimer's disease ( 30617256)
  • High light scatter reticulocyte count ( 27863252)
  • High light scatter reticulocyte percentage of red cells ( 27863252)
  • Immature fraction of reticulocytes ( 27863252)
  • Metabolite levels ( 23823483)
  • Plasma homocysteine levels ( 26519441)
  • Red cell distribution width ( 27863252)
  • Reticulocyte count ( 27863252)
  • Reticulocyte fraction of red cells ( 27863252)
Interacting Genes 33 interacting genes: ARAP3 BCAR1 CAPZA1 CBL CBLB CD2 CTTN FYN GRB2 GZMB HBP1 HCK HOXC11 KHDRBS1 MVB12A NPHS1 NPHS2 NR2C2 NR4A1 PDCD6IP PIK3R1 PKD2 PSTPIP1 PTGES3 RAB4A SH3GL2 SOS1 SOS2 SRC UBC UBE2I WTIP YES1 55 interacting genes: ABI1 ABI3 ANXA2 ATP6V1E1 BIN1 CAV1 CD19 CD2AP COPS3 CRK CRKL CSF1R EGFR EPS8 EPS8L1 EPS8L2 ERBB2 ERBB3 ESR1 FGFR1 FRS2 FYN GAB1 GRAP GRB2 HCK HDLBP HRAS ITSN1 ITSN2 LAT2 LCK MAPK1 MAPK3 MUC1 NCK1 NCK2 PACSIN1 PACSIN3 PIK3R2 PLCG1 PTPN11 PTPN6 RANBP9 RIT2 RRAS SH3BP5 SH3KBP1 SHC1 SIRPA SNX18 SNX9 SPTAN1 TNIK ZAP70
Entrez ID 23607 6654
HPRD ID 05026 01681
Ensembl ID ENSG00000198087 ENSG00000115904
Uniprot IDs Q9Y5K6 G5E9C8 Q07889
PDB IDs 2FEI 2J6F 2J6K 2J6O 2J7I 3AA6 3LK4 3U23 4WCI 4X1V 1AWE 1BKD 1DBH 1NVU 1NVV 1NVW 1NVX 1Q9C 1XD2 1XD4 1XDV 2II0 3KSY 4NYI 4NYJ 4NYM 4URU 4URV 4URW 4URX 4URY 4URZ 4US0 4US1 4US2 5OVD 5OVE 5OVF 5OVG 5OVH 5OVI 5WFO 5WFP 5WFQ 5WFR 6BVI 6BVJ 6BVK 6BVL 6BVM 6CUO 6CUP 6CUR 6D55 6D56 6D59 6D5E 6D5G 6D5H 6D5J 6D5L 6D5M 6D5V 6D5W 6EPL 6EPM 6EPN 6EPO 6EPP 6F08
Enriched GO Terms of Interacting Partners?
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