RHOQ and CDC42EP2

Number of citations of the paper that reports this interaction (PubMedID 10490598)
41

Data Source:
BioGRID (pull down, two hybrid)
HPRD (in vitro, two hybrid)

		RHOQ	CDC42EP2
Description		ras homolog family member Q	CDC42 effector protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Actin Filament Plasma Membrane Cell Cortex Golgi-associated Vesicle Membrane Cytoplasmic Vesicle Cell Projection Intracellular Membrane-bounded Organelle Membrane Raft Extracellular Exosome	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Endomembrane System Microtubule Cytoskeleton Membrane Phagocytic Vesicle
	Molecular Function	GTPase Activity Profilin Binding GTP Binding Protein Kinase Binding GBD Domain Binding	Opioid Peptide Activity GTPase Activator Activity Protein Binding GTP-Rho Binding
	Biological Process	Endocytosis Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Rho Protein Signal Transduction Insulin Receptor Signaling Pathway Regulation Of Cell Shape Cell Migration Cell Projection Assembly Actin Cytoskeleton Organization Cortical Cytoskeleton Organization Cortical Actin Cytoskeleton Organization Cellular Response To Insulin Stimulus Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Transcription By RNA Polymerase II GTP Metabolic Process Positive Regulation Of Glucose Import Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Filopodium Assembly Negative Regulation Of Protein Localization To Plasma Membrane	Actin Filament Organization Rho Protein Signal Transduction Regulation Of Cell Shape Actin Cytoskeleton Organization Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Pseudopodium Assembly Positive Regulation Of Protein Complex Assembly Positive Regulation Of GTPase Activity Cellular Response To Interferon-gamma
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Rho GTPase cycle RHO GTPases regulate CFTR trafficking	MAPK6/MAPK4 signaling
Drugs
Diseases
GWAS			Acne (severe) ( 24927181) Mean corpuscular volume ( 27863252)
Interacting Genes		18 interacting genes: CDC42BPG CDC42EP1 CDC42EP2 CDC42EP3 CDC42EP4 COPB1 COPG1 DOCK8 EXOC7 GOPC PARD6A PARD6B PFN1 PRKCI RAPGEF1 TRIP10 TRIP6 WASL	7 interacting genes: ARHGAP26 CDC42 NME7 RHOQ SEPTIN6 SEPTIN7 SNCA
Entrez ID		23433	10435
HPRD ID		05791	09363
Ensembl ID		ENSG00000119729	ENSG00000149798
Uniprot IDs		D6W5A7 P17081 V9HWD0	O14613
PDB IDs		2ATX
Enriched GO Terms of Interacting Partners?
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