DNMBP and WASL

Number of citations of the paper that reports this interaction (PubMedID 14506234)
64

Data Source:
HPRD (in vitro)

		DNMBP	WASL
Description		dynamin binding protein	WASP like actin nucleation promoting factor
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GO Annotations	Cellular Component	Golgi Apparatus Golgi Stack Cytoskeleton Cell-cell Junction Synapse Presynapse	Cell Nucleus Cytosol Actin Filament Plasma Membrane Actin Cytoskeleton Lamellipodium Actin Cap Actin Cortical Patch Endocytic Vesicle Membrane Cytoplasmic Vesicle Extracellular Exosome
	Molecular Function	Rho Guanyl-nucleotide Exchange Factor Activity Protein Binding	Protein Binding GTPase Regulator Activity Actin Filament Binding
	Biological Process	Aging Regulation Of Cell Shape Intracellular Signal Transduction	Actin Cortical Patch Assembly Endocytosis Vesicle Budding From Membrane Actin Polymerization Or Depolymerization Regulation Of Cell Shape Response To Bacterium Vesicle Organization Actin Filament Polymerization Actin Filament-based Movement Vesicle Transport Along Actin Filament Regulation Of Protein Localization Cellular Protein-containing Complex Localization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Positive Regulation Of Transcription By RNA Polymerase II Ephrin Receptor Signaling Pathway Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Actin Nucleation Cell Division Positive Regulation Of Filopodium Assembly Spindle Localization Actin Cortical Patch Localization Dendritic Spine Morphogenesis Membrane Organization Protein-containing Complex Assembly Negative Regulation Of Membrane Tubulation Positive Regulation Of Clathrin-dependent Endocytosis Negative Regulation Of Lymphocyte Migration Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Pathways			Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation NOSTRIN mediated eNOS trafficking Nephrin family interactions EPHB-mediated forward signaling EPHB-mediated forward signaling DCC mediated attractive signaling RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs Clathrin-mediated endocytosis FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS			Platelet count ( 22139419 27863252) Plateletcrit ( 27863252)
Interacting Genes		18 interacting genes: ACTA1 ARHGAP17 BUB1B CNN1 CYFIP2 DBN1 DNM1 ENAH EVL FASLG HSPA1B KHDRBS1 NCKAP1 RAPH1 VASP WASF1 WASL WIPF2	51 interacting genes: AASS ABL1 ACTG1 ACTR2 ACTR3 APBB1 APP ARPC3 BIN1 CDC42 CORO7 CTTN DNMBP EGFR EVL FCHSD2 FNBP1 FNBP1L GRB2 HP HSP90AA1 HSP90AB1 IPO5 ITSN1 ITSN2 LCK NCK1 NCK2 NCKIPSD PACSIN1 PACSIN2 PACSIN3 PFN1 PRMT2 PRPF40A PSTPIP1 PTK6 RHOJ RHOQ RNF8 RPL7AP66 SDCBP SH3GL3 SNX9 SRC TRIP10 VASP VIPR1 WIPF1 WIPF2 ZNF395
Entrez ID		23268	8976
HPRD ID		10918	05448
Ensembl ID		ENSG00000107554	ENSG00000106299
Uniprot IDs		A0A1B0GTX1 A0A1C7CYY6 B3KY33 Q6XZF7	O00401
PDB IDs		1UG1 1UHC 4CC2 4CC3 4CC4 4CC7 4GLM	2FF3 2LNH 2VCP 4CC2 4CC7
Enriched GO Terms of Interacting Partners?
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