JMJD6 and NAA50

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		JMJD6	NAA50
Description		jumonji domain containing 6, arginine demethylase and lysine hydroxylase	N-alpha-acetyltransferase 50, NatE catalytic subunit
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Plasma Membrane Ribonucleoprotein Complex	Nucleus Cytoplasm Cytosol NatA Complex Extracellular Exosome
	Molecular Function	Transcription Coactivator Activity RNA Binding Single-stranded RNA Binding Iron Ion Binding Protein Binding Demethylase Activity Histone Demethylase Activity Histone Demethylase Activity (H3-R2 Specific) Histone Demethylase Activity (H4-R3 Specific) Oxidative RNA Demethylase Activity Signaling Receptor Activity Identical Protein Binding Peptidyl-lysine 5-dioxygenase Activity P-TEFb Complex Binding	Peptide Alpha-N-acetyltransferase Activity Protein Binding N-acetyltransferase Activity H4 Histone Acetyltransferase Activity Peptidyl-lysine Acetyltransferase Activity
	Biological Process	Kidney Development Sprouting Angiogenesis MRNA Processing Protein Demethylation Cell Surface Receptor Signaling Pathway Heart Development RNA Splicing Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Lung Development T Cell Differentiation In Thymus Oxidative RNA Demethylation Macrophage Activation Recognition Of Apoptotic Cell Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Regulation Of MRNA Splicing, Via Spliceosome Erythrocyte Development Protein Homooligomerization Retina Development In Camera-type Eye Histone H3-R2 Demethylation Histone H4-R3 Demethylation	N-terminal Protein Amino Acid Acetylation Mitotic Sister Chromatid Cohesion Histone Acetylation Establishment Of Mitotic Sister Chromatid Cohesion Histone H4 Acetylation Mitotic Sister Chromatid Cohesion, Centromeric
Pathways		HDMs demethylate histones
Drugs
Diseases
GWAS		Retinal arteriolar caliber ( 23776548)	Prostate cancer ( 23535732)
Interacting Genes		27 interacting genes: AEBP2 ANKEF1 BAG5 C17orf97 CCNL1 CENPL DIP2A FGD5 FRMD6 GNA14 H2BC11 H3C1 H4C1 HMGXB4 LARP7 NAA50 NFIX NHP2 PRPF38A PSMC1 RSPO2 SLFN12 SLU7 STAC3 TAF1A U2AF1 ZNF451	4 interacting genes: BHLHE40 JMJD6 NAA10 NAA15
Entrez ID		23210	80218
HPRD ID		05371	14350
Ensembl ID		ENSG00000070495	ENSG00000121579
Uniprot IDs		Q6NYC1	E7EQ69 Q9GZZ1
PDB IDs		3K2O 3LD8 3LDB 6BNH 6GDY 6MEV	2OB0 2PSW 3TFY 4X5K
Enriched GO Terms of Interacting Partners?
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