FLT1 and PLCG1

  • Number of citations of the paper that reports this interaction (PubMedID 11312102)
  • 28
  • Data Source:
  • BioGRID (pull down, two hybrid)
  • HPRD (in vivo)

FLT1

PLCG1

Description fms related receptor tyrosine kinase 1 phospholipase C gamma 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Birth weight ( 31043758)
  • Body mass index ( 26426971)
  • Cognitive performance ( 19734545)
  • Coronary artery disease ( 29212778)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Coronary heart disease ( 23364394)
  • Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes 25 interacting genes: ATR CRK CTNNB1 FYN GRB2 KDR NCK1 NEDD4 NRP1 NRP2 PGF PIK3R1 PLCG1 PLCG2 PTK2 PTK2B PTPN11 SHC1 SHC2 SRPK1 STAT1 STAT3 VEGFA VEGFB YES1 108 interacting genes: ABL1 AGAP2 AGTR1 AKT1 ALK ARHGAP32 ARHGEF5 AXL BAG3 BCR BLNK BTK CBL CD22 CD28 CTSS DAB1 DAPP1 DDR1 DGKZ DNM1 DOK1 EEF1A1 EGFR EPHB2 EPOR ERBB2 ERBB3 FGFR1 FGFR2 FGFR4 FLT1 FYN GAB1 GAB2 GHR GIT1 GRAP GRB2 GRIN1 GRIN2A GRIN2B GSN GTF2H1 HCK INPP5D INSR IRS2 ITK KDR KHDRBS1 KIT LAT LAT2 LCK LCP2 LIFR LYN MAPT MET MST1R NCAM1 NCK1 NPM1 NTRK1 NTRK2 NTRK3 PAK1 PDGFRA PDGFRB PECAM1 PICALM PITPNA PKN2 PLD2 PRKD1 PTK2 PTPN11 PTPRJ RACK1 RET RHOA RHOU SELE SH2D2A SH3BP2 SHB SHC1 SNAP91 SOCS7 SOS1 SOS2 SRC SYK SYN1 SYNCRIP TEC TNK1 TRIM14 TRPC3 TRPM7 TUB USO1 VAV1 VAV3 VIL1 WAS ZAP70
Entrez ID 2321 5335
HPRD ID 01297 01398
Ensembl ID ENSG00000102755 ENSG00000124181
Uniprot IDs L7RSL3 P17948 P19174 Q4LE43 Q9UFY1
PDB IDs 1FLT 1QSV 1QSZ 1QTY 1RV6 2XAC 3HNG 4CKV 4CL7 5ABD 5EX3 5T89 1HSQ 2HSP 4EY0 4FBN
Enriched GO Terms of Interacting Partners?
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