SYT11 and SGTA

Number of citations of the paper that reports this interaction (PubMedID 21516116)
94

Data Source:
BioGRID (two hybrid)

		SYT11	SGTA
Description		synaptotagmin 11	small glutamine rich tetratricopeptide repeat containing alpha
Image		No pdb structure
GO Annotations	Cellular Component	Phagocytic Cup Cell Lysosome Lysosomal Membrane Trans-Golgi Network Plasma Membrane Synaptic Vesicle Postsynaptic Density Cell Junction Axon Dendrite Clathrin-coated Vesicle Membrane Vesicle Early Phagosome Neuron Projection Terminal Bouton Dendritic Spine Perikaryon Synapse Phagocytic Vesicle Perinuclear Region Of Cytoplasm Presynaptic Active Zone Membrane Recycling Endosome Recycling Endosome Membrane Excitatory Synapse Inhibitory Synapse Exocytic Vesicle Schaffer Collateral - CA1 Synapse Presynapse Integral Component Of Presynaptic Active Zone Membrane	Nucleus Cytoplasm Cytosol Membrane TRC Complex Extrinsic Component Of Synaptic Vesicle Membrane
	Molecular Function	SNARE Binding Phosphatidylserine Binding Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Clathrin Binding Translation Initiation Factor Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Beta-tubulin Binding	Protein Binding Identical Protein Binding Protein Self-association Molecular Adaptor Activity BAT3 Complex Binding
	Biological Process	Plasma Membrane Repair Vesicle Fusion Autophagy Learning Memory Regulation Of Dopamine Secretion Vesicle-mediated Transport Calcium Ion Regulated Exocytosis Regulation Of Calcium Ion-dependent Exocytosis Negative Regulation Of Dopamine Secretion Negative Regulation Of Endocytosis Negative Regulation Of Neurotransmitter Secretion Negative Regulation Of Cytokine Secretion Negative Regulation Of Phagocytosis Establishment Of Vesicle Localization Cellular Response To Calcium Ion Negative Regulation Of Interleukin-6 Secretion Negative Regulation Of Clathrin-dependent Endocytosis Negative Regulation Of Synaptic Vesicle Endocytosis Regulation Of Defense Response To Bacterium Negative Regulation Of Microglial Cell Activation Negative Regulation Of Tumor Necrosis Factor Secretion Negative Regulation Of Membrane Invagination Regulation Of Phagosome Maturation Positive Regulation Of Protein Localization To Phagocytic Vesicle Negative Regulation Of Clathrin-coated Pit Assembly Calcium Ion Regulated Lysosome Exocytosis	Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Viral Process Ubiquitin-dependent ERAD Pathway Chaperone-mediated Protein Folding Tail-anchored Membrane Protein Insertion Into ER Membrane Negative Regulation Of ER-associated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of ER-associated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Chaperone-mediated Protein Folding Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process
Pathways		Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis	Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 28892062) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Parkinson's disease ( 21292315 25064009) Serum cancer antigen 15.3 levels ( 31666285)
Interacting Genes		4 interacting genes: APPBP2 PRKN SGTA SYNCRIP	98 interacting genes: ADIPOQ ADRM1 AGR3 BAG6 BCL2L12 BTC C1QA C1QTNF1 C1QTNF6 C3orf52 CD79B CD99 CD99L2 CDH15 COL1A2 COL8A2 CSF1 CST1 CTSL CXCL8 EFEMP1 EFEMP2 ERP27 EVA1B F11R FERD3L FIP1L1 FKBP7 FXYD7 GABARAPL2 GAL GHR GIP GPX7 GRN GYPA HSP90AA1 HSP90AB1 HSPA13 HSPA4 HSPA8 IGL IGLC1 IRF3 IRF5 ITPRIPL1 KASH5 KRT6A KTN1 LAIR2 LAT MSMB MSTN MYDGF NAXD NME3 NR3C1 NXF1 PBXIP1 PCDHA4 PFN2 PGR PIAS1 PLAAT4 PPIB PPIC PPP1R3C PRAP1 PTN RPN1 SDC4 SERPINE1 SGCA SLPI SMAGP SOD3 SPP1 SPPL2A SRGN SYT11 SYT4 TFF3 TFRC TGFA TMEM174 TMEM31 TMPO TMUB2 TNFRSF13B TNFRSF1A TWSG1 TXNDC12 UBL4A UPK3A VIP WBP1L ZG16 ZG16B
Entrez ID		23208	6449
HPRD ID		12289	04568
Ensembl ID		ENSG00000132718	ENSG00000104969
Uniprot IDs		Q9BT88	O43765
PDB IDs			2VYI 4CPG 4GOD 4GOE 4GOF
Enriched GO Terms of Interacting Partners?
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