RCOR1 and FOXK2

Number of citations of the paper that reports this interaction (PubMedID 27773593)
18

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, biochemical, pull down)

		RCOR1	FOXK2
Description		REST corepressor 1	forkhead box K2
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcriptional Repressor Complex DNA Repair Complex	Nuclear Chromatin Cell Nucleus Nucleoplasm Mitochondrion Intracellular Membrane-bounded Organelle
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Transcription Factor Binding Transcription Regulatory Region DNA Binding	Magnesium Ion Binding Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Blood Coagulation Viral Process Negative Regulation Of Transcription, DNA-templated Histone H4 Deacetylation	Negative Regulation Of Transcription By RNA Polymerase II Cellular Glucose Homeostasis Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Autophagy Regulation Of Glucose Metabolic Process Protein Deubiquitination Response To Starvation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Canonical Glycolysis
Pathways		HDACs deacetylate histones Regulation of PTEN gene transcription Factors involved in megakaryocyte development and platelet production	UCH proteinases
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Body mass index ( 26426971) Immature fraction of reticulocytes ( 27863252) Mean platelet volume ( 27863252) Multiple sclerosis ( 31604244) Platelet count ( 22139419 27863252) Plateletcrit ( 27863252)	Heel bone mineral density ( 30598549) Lean body mass ( 28552196) Letter-number span reordering ( 31596458) Red cell distribution width ( 27863252 28957414) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252)
Interacting Genes		12 interacting genes: CTBP1 FOXK2 H3-4 HDAC2 KDM1A PHF21A REST SMARCE1 SNAI1 SUB1 SUMO2 ZMYM2	10 interacting genes: ESR1 HCFC1 IL2 MTA3 RBBP4 RBBP7 RCOR1 SIN3A TBL1X TBL1XR1
Entrez ID		23186	3607
HPRD ID		09645	00982
Ensembl ID		ENSG00000089902	ENSG00000141568
Uniprot IDs		Q9UKL0	Q01167
PDB IDs		2IW5 2UXN 2UXX 2V1D 2X0L 2XAF 2XAG 2XAH 2XAJ 2XAQ 2XAS 2Y48 3ZMS 3ZMT 3ZMU 3ZMV 3ZMZ 3ZN0 3ZN1 4BAY 4KUM 4UV8 4UV9 4UVA 4UVB 4UVC 4UXN 4XBF 5H6Q 5H6R 5L3B 5L3C 5L3D 5L3E 5L3F 5L3G 5LBQ 5LGN 5LGT 5LGU 5LHG 5LHH 5LHI 5X60 5YJB	1JXS 2C6Y
Enriched GO Terms of Interacting Partners?
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