SEPTIN6 and CDC42EP3

Number of citations of the paper that reports this interaction (PubMedID 11584266)
73

Data Source:
BioGRID (pull down)

		SEPTIN6	CDC42EP3
Description		septin 6	CDC42 effector protein 3
Image			No pdb structure
GO Annotations	Cellular Component	Condensed Chromosome Kinetochore Spindle Septin Ring Synaptic Vesicle Microtubule Cytoskeleton Midbody Septin Complex Cell Division Site Cleavage Furrow Septin Collar Axon Terminus Sperm Annulus	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Endomembrane System Actin Cytoskeleton
	Molecular Function	GTPase Activity Protein Binding GTP Binding Molecular Adaptor Activity	Protein Binding Cytoskeletal Regulatory Protein Binding GTP-Rho Binding
	Biological Process	Mitotic Cytokinesis Spermatogenesis Viral Process Cell Differentiation Cellular Protein Localization Cilium Assembly Cytoskeleton-dependent Cytokinesis	Signal Transduction Rho Protein Signal Transduction Regulation Of Cell Shape Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Pseudopodium Assembly
Pathways			MAPK6/MAPK4 signaling
Drugs
Diseases
GWAS			Facial attractiveness (male raters) ( 30946739) Height ( 28552196 20881960 23563607 31562340) Night sleep phenotypes ( 27126917) Rheumatoid arthritis ( 30891314) Total ventricular volume (Alzheimer's disease interaction) ( 21116278)
Interacting Genes		14 interacting genes: CDC42EP2 CDC42EP3 CRK KDM1A MORN4 NSD3 PLEKHF2 RHOU S100A4 SEPTIN1 SEPTIN2 SEPTIN9 SH3KBP1 TK1	11 interacting genes: CDC42 DAPK1 LRRK1 LRRK2 MFHAS1 RHOQ SEPTIN6 SEPTIN7 SNCA SRPK1 UMPS
Entrez ID		23157	10602
HPRD ID		06716	09364
Ensembl ID		ENSG00000125354	ENSG00000163171
Uniprot IDs		B1AMS2 Q14141 Q541S4 Q548C9	Q9UKI2
PDB IDs		2QAG
Enriched GO Terms of Interacting Partners?
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