NFASC and SDCBP2

Number of citations of the paper that reports this interaction (PubMedID 11152476)
34

Data Source:
HPRD (in vitro, two hybrid)

		NFASC	SDCBP2
Description		neurofascin	syndecan binding protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Dendrite Paranodal Junction Node Of Ranvier Paranode Region Of Axon Axon Initial Segment Schwann Cell Microvillus Ficolin-1-rich Granule Membrane	Nucleolus Cytoplasm Plasma Membrane Nuclear Speck Extracellular Exosome
	Molecular Function	Protein Binding Protein Domain Specific Binding Protein Binding Involved In Heterotypic Cell-cell Adhesion	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Protein C-terminus Binding Identical Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process	Protein Localization To Paranode Region Of Axon Axon Guidance Peripheral Nervous System Development Transmission Of Nerve Impulse Paranodal Junction Assembly Heterotypic Cell-cell Adhesion Myelination Neutrophil Degranulation Clustering Of Voltage-gated Sodium Channels Synapse Organization Protein Localization To Juxtaparanode Region Of Axon Protein Localization To Plasma Membrane	Nervous System Development Cell Proliferation Intracellular Signal Transduction Intracellular Transport
Pathways		Interaction between L1 and Ankyrins Neurofascin interactions Neurofascin interactions Neutrophil degranulation
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Blood protein levels ( 30072576 29875488 28240269) Clozapine-induced agranulocytosis ( 25187353) Dental caries ( 23064961) Diisocyanate-induced asthma ( 25918132) Disrupted circadian rhythm (low relative amplitude of rest-activity cycles) ( 30120083) General risk tolerance (MTAG) ( 30643258) Mean platelet volume ( 27863252) Regular attendance at a religious group ( 29970889)	Estimated glomerular filtration rate ( 31152163) Metabolite levels ( 23823483)
Interacting Genes		10 interacting genes: ANK1 CNTNAP1 DCX NRCAM SCN1B SCN3B SCNN1B SDCBP SDCBP2 TNR	44 interacting genes: ADAP1 ARF4 BEND7 C1orf35 CT45A3 CT45A5 CTH DPPA2 EIF1AD FAM133A FAM13C FAM9B FBXO28 GABRA3 LGALS14 LGALS2 LYAR MED4 NFASC NKAPD1 NPM2 NRXN1 NUF2 PAFAH1B3 PRPF38A PRPF40A PRR13 PTMS RNPS1 RPL22 SDCBP SEC23A SREK1IP1 TDO2 THAP6 TIFA TM4SF1 TNP1 TRAF1 YTHDC1 ZCCHC10 ZCCHC17 ZNF581 ZRSR2
Entrez ID		23114	27111
HPRD ID		12372	18032
Ensembl ID		ENSG00000163531	ENSG00000125775
Uniprot IDs		B4DRH7 O94856	Q9H190
PDB IDs		3P3Y 3P40
Enriched GO Terms of Interacting Partners?
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