RIMS1 and CACNA1C

  • Number of citations of the paper that reports this interaction (PubMedID 11438519)
  • 15
  • Data Source:
  • HPRD (in vitro)

RIMS1

CACNA1C

Description regulating synaptic membrane exocytosis 1 calcium voltage-gated channel subunit alpha1 C
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced) ( 24236485)
  • Adverse response to chemotherapy (amenorrhea) in breast cancer ( 31371054)
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Bipolar disorder ( 31043756)
  • Chronotype ( 30696823)
  • Cognitive performance ( 20125193)
  • Lung cancer ( 28604730)
  • Lung cancer in never smokers ( 28604730)
  • Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
  • Response to mTOR inhibitor (rapamycin) ( 24009623)
  • Rosacea symptom severity ( 29771307)
  • Schizophrenia ( 25056061 29483656 30285260)
  • Squamous cell lung carcinoma ( 28604730)
  • Acoustic startle blink response ( 25387708)
  • Adventurousness ( 30643258)
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Aortic root size ( 28394258)
  • Atypical femoral fracture in phosphonate treatment ( 31006051)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
  • Bipolar disorder ( 18711365 31043756 28072414 20351715)
  • Bipolar disorder or major depressive disorder ( 20351715)
  • Bipolar I disorder ( 31043756)
  • Broad depression or bipolar disorder ( 30626913)
  • Broad depression or schizophrenia ( 30626913)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Diastolic blood pressure ( 30224653)
  • Exploratory eye movement dysfunction in schizophrenia (cognitive search score) ( 26242244)
  • Fractional exhaled nitric oxide (childhood) ( 24315451)
  • General risk tolerance (MTAG) ( 30643258)
  • Heel bone mineral density ( 30598549 28869591)
  • Hematocrit ( 27863252)
  • Hemoglobin concentration ( 27863252)
  • Lumbar spine bone mineral density (integral) ( 27476799)
  • Lumbar spine bone mineral density (trabecular) ( 27476799)
  • Medication use (agents acting on the renin-angiotensin system) ( 31015401)
  • Perceived intensity of aspartame ( 31005972)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale) ( 28525603)
  • Psychosis proneness (hypomanic personality scale) ( 28525603)
  • Red blood cell count ( 29403010 27863252)
  • Red blood cell traits ( 23222517)
  • Response to olanzapine in schizophrenia ( 29503163)
  • Resting heart rate ( 29769521 27798624)
  • Schizophrenia ( 28991256 25056061 21926974 29483656 22688191 30285260 23974872)
  • Schizophrenia or bipolar disorder ( 24280982)
  • Sensorimotor dexterity ( 31596458)
  • Short-term memory (digit-span task) ( 30741946)
  • Sleep quality ( 23728906)
  • Warfarin maintenance dose ( 18535201)
Interacting Genes 15 interacting genes: CACNA1B CACNA1C CAMK2A ERC1 ERC2 RAB10 RAB26 RAB27A RAB37 RAB3A SNAP25 STX1A SYT1 UNC13B YWHAH 11 interacting genes: CABP1 CACNB3 COPS5 GNB1 HDAC4 PCBD1 PPM1A PRKACA RIMS1 RYR2 SRI
Entrez ID 22999 775
HPRD ID 09435 00246
Ensembl ID ENSG00000079841 ENSG00000151067
Uniprot IDs B7Z7W2 B7Z9Z3 Q3ZCW0 Q86UR5 A0A0A0MR67 A0A0A0MSA1 F5H522 Q13936 Q59GU3 Q5V9X9
PDB IDs 2CSS 1T0J 2BE6 2F3Y 2F3Z 2LQC 3G43 3OXQ 5V2P 5V2Q 6C0A 6DAD 6DAE 6DAF
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?