MAPRE3 and EIF4E2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		MAPRE3	EIF4E2
Description		microtubule associated protein RP/EB family member 3	eukaryotic translation initiation factor 4E family member 2
Image
GO Annotations	Cellular Component	Cytoplasm Microtubule Organizing Center Microtubule Midbody Microtubule Plus-end Spindle Midzone Mitotic Spindle Astral Microtubule End	Cytosol MRNA Cap Binding Complex Eukaryotic Translation Initiation Factor 4F Complex
	Molecular Function	Protein Binding Microtubule Binding Protein C-terminus Binding Protein Kinase Binding Identical Protein Binding Microtubule Plus-end Binding	RNA Cap Binding RNA 7-methylguanosine Cap Binding RNA Binding Translation Initiation Factor Activity Protein Binding Translation Factor Activity, RNA Binding Ubiquitin Protein Ligase Binding
	Biological Process	Protein Localization Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Microtubule Polymerization Protein Localization To Microtubule Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Protein Kinase Activity Positive Regulation Of Transcription, DNA-templated Spindle Assembly Cell Division Positive Regulation Of Microtubule Plus-end Binding Protein Localization To Microtubule Plus-end	In Utero Embryonic Development Translational Initiation Negative Regulation Of Translation
Pathways			ISG15 antiviral mechanism
Drugs
Diseases
GWAS		Estimated glomerular filtration rate in non-diabetics ( 31451708) Post bronchodilator FEV1/FVC ratio ( 26634245)	Height ( 25282103) Non-small cell lung cancer (survival) ( 21079520)
Interacting Genes		22 interacting genes: APC2 AURKA AURKB CLASP1 DCTN2 DOK4 EIF4E2 FXR2 GTSE1 JUN KIF19 LMO2 MAPRE1 MAPRE2 PSMA1 PSMB1 RAB1A SDCBP SIAH1 SLAIN1 TROAP TXN2	51 interacting genes: ADAMTSL4 AMOTL2 APP ARIH1 CAB39 CARD9 CBY2 CCL24 CDR2 EIF4EBP1 EIF4EBP3 EIF4ENIF1 FBXO25 GIGYF1 HOMEZ KRT13 KRT19 KRT20 KRT31 KRT40 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP4-12 LZTS2 MAGED1 MAPRE3 MDFI MIPOL1 MVK MYOG NECAB2 NOTCH2NLA PDE4DIP PRDM14 REL SAG SP140 SPAG5 SPRY2 TADA2A TCF4 TGFBRAP1 TLE5 TMCC2 TRIM27 TRIM54 UBXN11 USHBP1 USP54 ZBTB9
Entrez ID		22924	9470
HPRD ID		16156	05798
Ensembl ID		ENSG00000084764	ENSG00000135930
Uniprot IDs		Q9UPY8	B8ZZ50 B8ZZL3 B9A023 O60573 Q53RG0 Q59FE1
PDB IDs		1WYO 3CO1 3JAK 3JAL 3JAR 3TQ7	2JGB 2JGC 5NVK 5NVL 5NVM 5NVN 5XLN
Enriched GO Terms of Interacting Partners?
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