SACM1L and COPA

Number of citations of the paper that reports this interaction (PubMedID 14527956)
42

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		SACM1L	COPA
Description		SAC1 like phosphatidylinositide phosphatase	COPI coat complex subunit alpha
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Integral Component Of Membrane	Golgi Membrane Extracellular Space Cytoplasm Endoplasmic Reticulum Membrane Cytosol Membrane COPI Vesicle Coat Transport Vesicle Growth Cone Extracellular Exosome
	Molecular Function	Phosphatidylinositol-3-phosphatase Activity Protein Binding Phosphatase Activity Phosphatidylinositol Phosphate 4-phosphatase Activity Phosphatidylinositol-4-phosphate Phosphatase Activity	MRNA Binding Hormone Activity Structural Molecule Activity
	Biological Process	Phosphatidylinositol Biosynthetic Process Phosphatidylinositol Dephosphorylation	Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To ER Intra-Golgi Vesicle-mediated Transport Signal Transduction Pancreatic Juice Secretion Protein Localization To Axon Protein Localization To Cell Leading Edge
Pathways		Synthesis of PIPs at the ER membrane Synthesis of PIPs at the Golgi membrane	COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Response to anti-depressant treatment in major depressive disorder ( 22041458)	Breast size ( 27182965)
Interacting Genes		6 interacting genes: COPA COPB2 COPG1 CREB3 LMNA PRKCA	14 interacting genes: ARCN1 ARFGAP1 COPB2 COPE MTNR1B PDGFRB SACM1L SCYL1 SLC25A11 STX8 TMED10 TMED2 WBP1 WBP2
Entrez ID		22908	1314
HPRD ID		07587	03564
Ensembl ID		ENSG00000211456	ENSG00000122218
Uniprot IDs		B4DVV3 E9PGZ4 Q9NTJ5	P53621
PDB IDs			6PBG 6TZT 6U3V
Enriched GO Terms of Interacting Partners?
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