CLSTN1 and TOPBP1

Number of citations of the paper that reports this interaction (PubMedID 12421765)
39

Data Source:
HPRD (two hybrid)

		CLSTN1	TOPBP1
Description		calsyntenin 1	DNA topoisomerase II binding protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Extracellular Region Nucleus Endoplasmic Reticulum Membrane Cell Surface Cell Junction Postsynaptic Membrane Postsynaptic Endosome Glutamatergic Synapse GABA-ergic Synapse Integral Component Of Postsynaptic Density Membrane Integral Component Of Spine Apparatus Membrane	Condensed Nuclear Chromosome Spindle Pole Male Germ Cell Nucleus Nucleus Nucleoplasm Chromosome Cytoplasm Microtubule Organizing Center Plasma Membrane Actin Cytoskeleton Nuclear Body PML Body Intracellular Membrane-bounded Organelle
	Molecular Function	Amyloid-beta Binding Calcium Ion Binding Protein Binding Kinesin Binding X11-like Protein Binding	DNA Binding Protein Binding Protein C-terminus Binding Identical Protein Binding
	Biological Process	Regulation Of Cell Growth Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Positive Regulation Of Synaptic Transmission Positive Regulation Of Synapse Assembly Regulation Of Synapse Maturation Neurotransmitter Receptor Transport To Postsynaptic Membrane Vesicle-mediated Transport In Synapse	DNA Metabolic Process DNA Replication DNA Replication Initiation DNA Repair Cellular Response To DNA Damage Stimulus Mitotic G2 DNA Damage Checkpoint Response To Ionizing Radiation Mitotic DNA Replication Checkpoint Regulation Of Signal Transduction By P53 Class Mediator
Pathways			HDR through Single Strand Annealing (SSA) Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Regulation of TP53 Activity through Phosphorylation G2/M DNA damage checkpoint
Drugs
Diseases
GWAS			Iron status biomarkers ( 19084217)
Interacting Genes		14 interacting genes: APBA2 APBB1 BAHCC1 COL17A1 KIF2A KLC1 KLC2 MCM3AP MDM2 PRNP SETDB1 SLK TOPBP1 TRIP12	32 interacting genes: ABL1 AKT1 ATM BLM BMPR2 BRIP1 CDC45 CHEK1 CLSTN1 E2F1 ESR1 FHL3 GINS1 HUS1 PML POLE PPHLN1 PPP1CC RAD1 RAD9A RAI1 RBBP8 RHNO1 SF3B2 SMARCAD1 TBC1D4 TCFL5 TEX11 TICRR TOP2B UBR5 ZBTB17
Entrez ID		22883	11073
HPRD ID		10837	09678
Ensembl ID		ENSG00000171603	ENSG00000163781
Uniprot IDs		B4E3Q1 O94985	A0AV47 A7E2X7 Q05BV8 Q92547
PDB IDs			1WF6 2XNH 2XNK 3AL2 3AL3 3JVE 3OLC 3PD7 3UEN 3UEO 6RML 6RMM
Enriched GO Terms of Interacting Partners?
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