TFEC and DEFB127

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TFEC	DEFB127
Description		transcription factor EC	defensin beta 127
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleoplasm	Cellular_component Extracellular Region
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Protein Dimerization Activity	Protein Binding
	Biological Process	Cellular Response To Heat Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Nucleic Acid-templated Transcription	Defense Response To Bacterium Innate Immune Response Defense Response To Gram-negative Bacterium Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Pathways			Beta defensins Defensins
Drugs
Diseases
GWAS		Body mass index ( 28892062) Chronotype ( 30696823) General risk tolerance (MTAG) ( 30643258) Height ( 28552196) Intraocular pressure ( 29617998 29785010 29235454) Number of sexual partners ( 30643258) Tonsillectomy ( 27182965 28928442)
Interacting Genes		8 interacting genes: DCK DEFB127 HNRNPA1 MITF NAPB TFE3 TFEB ZMAT2	2 interacting genes: LMNA TFEC
Entrez ID		22797	140850
HPRD ID		05294	10877
Ensembl ID		ENSG00000105967	ENSG00000088782
Uniprot IDs		O14948	Q9H1M4
PDB IDs
Enriched GO Terms of Interacting Partners?
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