FHIT and CTNNB1

  • Number of citations of the paper that reports this interaction (PubMedID 18077326)
  • 24
  • Data Source:
  • BioGRID (affinity chromatography technology, pull down, imaging technique)

FHIT

CTNNB1

Description fragile histidine triad diadenosine triphosphatase catenin beta 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to lamotrigine and phenytoin ( 22379998)
  • Aortic root size ( 21223598)
  • Asparaginase-induced acute pancreatitis in acute lymphoblastic leukemia (onset time) ( 27114598)
  • Asperger disorder ( 21182207)
  • Attention deficit hyperactivity disorder ( 18821565)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Blood pressure ( 24954895)
  • Blood protein levels ( 30072576)
  • BMI (adjusted for smoking behaviour) ( 28443625)
  • BMI in non-smokers ( 28443625)
  • BMI in smokers ( 28443625)
  • Body mass index ( 28552196 26961502 28892062 25673413 28448500)
  • Body mass index (joint analysis main effects and physical activity interaction) ( 28448500)
  • Body mass index (joint analysis main effects and smoking interaction) ( 28443625)
  • Body mass index in physically active individuals ( 28448500)
  • Broad depression or schizophrenia ( 30626913)
  • Bronchopulmonary dysplasia ( 23897914)
  • Caudal anterior-cingulate cortex volume ( 31530798)
  • Cognitive function ( 25644384)
  • Conotruncal heart defects ( 24800985)
  • Depressive symptom measurement or major depressive disorder ( 28049566)
  • Differentiated thyroid cancer ( 28703219)
  • HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535)
  • Hip circumference ( 28552196)
  • Intracranial aneurysm ( 29531279)
  • Iris color (L* coordinate) ( 30895295)
  • Irritable bowel syndrome ( 29673008)
  • Lung function (maximal voluntary ventilation) ( 29095316)
  • Major coronary event in cardiovascular disease (time to event) (darapladib treatment interaction) ( 28753643)
  • Major coronary event in placebo-treated cardiovascular disease (time to event) ( 28753643)
  • Major depressive disorder ( 20125088)
  • Methadone dose in opioid dependence ( 28115739)
  • Myopia (pathological) ( 23049088)
  • Orofacial clefts ( 22419666)
  • Papillary thyroid cancer ( 28703219)
  • Pars triangularis volume ( 31530798)
  • Photic sneeze reflex ( 27182965)
  • Postoperative myocardial infarction after cardiac surgery ( 30678657)
  • Response to amphetamines ( 22952603)
  • Response to citalopram treatment ( 22760553)
  • Schizophrenia ( 30285260)
  • Urinary metabolite levels in chronic kidney disease ( 29545352)
  • Waist circumference ( 28552196)
  • Weight ( 28552196)
Interacting Genes 9 interacting genes: CTNNB1 FDXR GSN HSPD1 RAB40B REL SRC TRIM23 UBE2I 187 interacting genes: ACP1 AJAP1 AKT1 AMER1 APC APC2 APP AR ARFGEF1 ARHGAP32 ASH2L AXIN1 AXIN2 BCL3 BCL6 BCL9 BCL9L BOC BRCA1 BTRC CA9 CARM1 CASP3 CASP8 CBL CBY1 CCND1 CDC27 CDC34 CDC73 CDH1 CDH11 CDH15 CDH16 CDH2 CDH24 CDH3 CDH5 CDH7 CDH8 CDH9 CDK2 CDK5R1 CDK6 CDON CEBPA CHD8 CHUK CREBBP CSNK1A1 CSNK1D CSNK2A1 CSNK2B CTNNA1 CTNNA3 CTNNBIP1 CTNND2 DLG5 DSC3 DVL1 DVL3 EGFR ELAVL1 EP300 ERBB2 ERBIN ESR1 EZR FBXW2 FER FHIT FHL2 FLT1 FOXO1 FOXO4 FSCN1 FUS FYN GLIS2 GNA13 GRIK2 GRIN1 GRIN2D GSK3B H1-2 HIF1A HNF1A HUWE1 IGF2BP1 IKBKB IQGAP1 JADE1 KAT2A KAT2B KDR KMT2A KMT2D LATS2 LEF1 LEO1 MAGI1 MAGI2 MAP3K2 MAPK8 MAPK9 MEN1 MET MITF MUC1 NCOA2 NDRG1 NEK2 NEURL2 NF2 NFKB1 NOTCH1 NR5A1 PECAM1 PICK1 PIK3R1 PIN1 PITX2 PKD1 PKM PKP2 PLK1 PPM1A PRKCG PSEN1 PSEN2 PTGS2 PTPN1 PTPN13 PTPN14 PTPN6 PTPRF PTPRJ PTPRK PTPRM PTPRU PTPRZ1 PYGO1 RAPGEF2 RBBP5 RET RUVBL1 RUVBL2 RXRA SALL1 SLC9A3R1 SMAD2 SMAD3 SMAD4 SMAD7 SMARCA4 SMARCA5 SMURF1 SOX1 SOX17 SP1 SPN SRC STUB1 TAX1BP3 TBL1X TCF3 TCF4 TCF7L1 TCF7L2 TFAP2A TGFBR1 TGFBR2 TLE1 TRIM33 TRIP10 TRRAP UBE2B UBE2D1 UBE2R2 UBE2S UBE3A UHRF2 USP2 USP7 USP9X ZFYVE9 ZIC3
Entrez ID 2272 1499
HPRD ID 03096 00286
Ensembl ID ENSG00000189283 ENSG00000168036
Uniprot IDs A0A024R366 P49789 A0A024R2Q3 B4DGU4 P35222
PDB IDs 1FHI 1FIT 2FHI 2FIT 3FIT 4FIT 5FIT 6FIT 1G3J 1JDH 1JPW 1LUJ 1P22 1QZ7 1T08 1TH1 2G57 2GL7 2Z6H 3DIW 3FQN 3FQR 3SL9 3SLA 3TX7 4DJS 6M90 6M91 6M92 6M93 6M94 6O9B 6O9C
Enriched GO Terms of Interacting Partners?
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