FDPS and EIF4ENIF1

Number of citations of the paper that reports this interaction (PubMedID 19060904)
283

Data Source:
BioGRID (two hybrid)

		FDPS	EIF4ENIF1
Description		farnesyl diphosphate synthase	eukaryotic translation initiation factor 4E nuclear import factor 1
Image
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol	P-body Nucleus Cytoplasm Cytosol Membrane PML Body Nuclear Speck Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Binding Dimethylallyltranstransferase Activity Geranyltranstransferase Activity Metal Ion Binding	RNA Binding MRNA Binding Nuclear Export Signal Receptor Activity Protein Binding
	Biological Process	Cholesterol Biosynthetic Process Viral Process Geranyl Diphosphate Biosynthetic Process Farnesyl Diphosphate Biosynthetic Process Regulation Of Cholesterol Biosynthetic Process	Protein Transport Negative Regulation Of Translation Stem Cell Population Maintenance Negative Regulation Of Neuron Differentiation Nuclear Export
Pathways		Cholesterol biosynthesis Activation of gene expression by SREBF (SREBP)
Drugs		Pamidronate Zoledronic acid Alendronic acid Ibandronate Risedronate Dimethylallyl Diphosphate Isopentyl Pyrophosphate Geranyl Diphosphate ISOPENTENYL PYROPHOSPHATE FARNESYL DIPHOSPHATE Geranylgeranyl diphosphate
Diseases
GWAS		Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908)	Age-related hearing impairment ( 24939585)
Interacting Genes		5 interacting genes: ATXN1 CREB3 EIF4ENIF1 FBN2 FGFR1	21 interacting genes: ATXN1 CDK6 DDX6 DEF6 DTX2 EFHC1 EIF3E EIF4E EIF4E2 FANCL FDPS HNRNPF KRT19 LSM14A MGAT5B NIN OIP5 SMAD3 SPAG5 TTC19 TXLNA
Entrez ID		2224	56478
HPRD ID		00606	10456
Ensembl ID		ENSG00000160752	ENSG00000184708
Uniprot IDs		A0A087X090 P14324	A0A024R1K0 Q9NRA8
PDB IDs		1YQ7 1YV5 1ZW5 2F7M 2F89 2F8C 2F8Z 2F92 2F94 2F9K 2OPM 2OPN 2QIS 2RAH 2VF6 3B7L 3CP6 3N1V 3N1W 3N3L 3N45 3N46 3N49 3N5H 3N5J 3N6K 3RYE 3S4J 4DEM 4GA3 4H5C 4H5D 4H5E 4JVJ 4KFA 4KPD 4KPJ 4KQ5 4KQS 4KQU 4L2X 4LFV 4LPG 4LPH 4N1Z 4N9U 4NFI 4NFJ 4NFK 4NG6 4NKE 4NKF 4NUA 4OGU 4P0V 4P0W 4P0X 4PVX 4PVY 4Q23 4QPF 4QXS 4RXA 4XQR 4XQS 4XQT 5CG5 5CG6 5DGM 5DGN 5DGS 5DIQ 5DJP 5DJR 5DJV 5JA0 5JUZ 5JV0 5JV1 5JV2 5KSX 5YGI 6N7Y 6N7Z 6N82 6N83 6OAG 6OAH	5ANR 6F9W
Enriched GO Terms of Interacting Partners?
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