FAT1 and NOXA1

Number of citations of the paper that reports this interaction (PubMedID 28129444)
3

Data Source:
BioGRID (two hybrid)

		FAT1	NOXA1
Description		FAT atypical cadherin 1	NADPH oxidase activator 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Focal Adhesion Apical Plasma Membrane Lamellipodium Filopodium Perinuclear Region Of Cytoplasm Extracellular Exosome	Cytosol NADPH Oxidase Complex
	Molecular Function	Calcium Ion Binding Protein Binding	Protein Binding Superoxide-generating NADPH Oxidase Activator Activity SH3 Domain Binding Enzyme Binding Rac GTPase Binding
	Biological Process	Epithelial Cell Morphogenesis Actin Filament Organization Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Establishment Or Maintenance Of Cell Polarity Cell-cell Signaling Anatomical Structure Morphogenesis Cell Migration Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Camera-type Eye Morphogenesis Cell-cell Adhesion	Superoxide Metabolic Process Regulation Of Hydrogen Peroxide Metabolic Process Superoxide Anion Generation Positive Regulation Of Catalytic Activity Regulation Of Respiratory Burst
Pathways			RHO GTPases Activate NADPH Oxidases WNT5:FZD7-mediated leishmania damping
Drugs
Diseases
GWAS		Alzheimer disease and age of onset ( 26830138) Carotid plaque burden ( 28282560) Chronotype ( 26955885) Heel bone mineral density ( 30598549) Macular thickness ( 30535121) Major depressive disorder ( 29317602) Medication use (calcium channel blockers) ( 31015401) Morning vs. evening chronotype ( 26955885) Obesity ( 21552555) PR interval ( 30046033) Urinary albumin-to-creatinine ratio ( 31630189)	Response to fenofibrate (total cholesterol levels) ( 27002377)
Interacting Genes		12 interacting genes: CLK1 ENAH HOMER1 HOMER3 IGLL1 MT-ND1 NOXA1 SORBS2 TRAF4 TRIM14 UBC VASP	14 interacting genes: CACNA1A EP300 FAT1 MAPK1 MAPK11 NCF1 NOX1 NOXO1 PRKACA PRKCA PRKCG RAC1 RAC2 RIMBP3
Entrez ID		2195	10811
HPRD ID		02986	17644
Ensembl ID		ENSG00000083857	ENSG00000188747
Uniprot IDs		Q14517	Q86UR1
PDB IDs
Enriched GO Terms of Interacting Partners?
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