FARSA and ABI3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		FARSA	ABI3
Description		phenylalanyl-tRNA synthetase subunit alpha	ABI family member 3
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Phenylalanine-tRNA Ligase Complex Membrane	Cytoplasm Membrane Lamellipodium
	Molecular Function	TRNA Binding RNA Binding Phenylalanine-tRNA Ligase Activity Protein Binding ATP Binding	Protein Binding SH3 Domain Binding Identical Protein Binding
	Biological Process	TRNA Aminoacylation For Protein Translation Phenylalanyl-tRNA Aminoacylation Protein Heterotetramerization	Peptidyl-tyrosine Phosphorylation Regulation Of Cell Migration
Pathways		Cytosolic tRNA aminoacylation
Drugs		L-Phenylalanine
Diseases
GWAS		Clozapine-induced agranulocytosis ( 25187353) Estimated glomerular filtration rate ( 31152163) Red blood cell count ( 27863252) Red blood cell traits ( 23222517) Type 2 diabetes ( 30297969)	Alzheimer's disease (late onset) ( 28714976) Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Asthma ( 31619474) Family history of Alzheimer's disease ( 30617256) Prostate cancer ( 23535732)
Interacting Genes		9 interacting genes: A2M ABI3 APOE ECSIT ESR1 GORAB HNRNPR RNF32 TDGF1	36 interacting genes: ABI3BP ACTN3 ARMC7 CEP170P1 CEP44 CYFIP2 DTNB DTNBP1 EIF3H ENAH EVL FARSA FBF1 GRB2 HOMER1 HOMER3 KANK2 KIAA0408 KLC3 KLC4 KRT13 KRT15 MAGEA12 MRFAP1L1 NCK2 NUP58 PAK1 PAK2 PSMA1 RUNX1T1 SNAP23 SOS1 TMEM147 VASP WAS WASF2
Entrez ID		2193	51225
HPRD ID		04227	05900
Ensembl ID		ENSG00000179115	ENSG00000108798
Uniprot IDs		Q6IBR2 Q9Y285	Q9P2A4
PDB IDs		3L4G
Enriched GO Terms of Interacting Partners?
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