FANCD2 and FANCC

Number of citations of the paper that reports this interaction (PubMedID 11751423)
13

Data Source:
HPRD (in vivo)

		FANCD2	FANCC
Description		FA complementation group D2	FA complementation group C
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Condensed Chromosome Nucleus Nucleoplasm Nucleolus Cytosol Nuclear Body	Nucleus Nucleoplasm Cytoplasm Cytosol Fanconi Anaemia Nuclear Complex
	Molecular Function	Protein Binding DNA Polymerase Binding	Protein Binding
	Biological Process	Synapsis Gamete Generation Response To Gamma Radiation Intra-S DNA Damage Checkpoint Cellular Response To Oxidative Stress Interstrand Cross-link Repair Regulation Of Regulatory T Cell Differentiation Brain Morphogenesis Regulation Of Inflammatory Response Regulation Of DNA-binding Transcription Factor Activity Neuronal Stem Cell Population Maintenance Double-strand Break Repair Involved In Meiotic Recombination Regulation Of CD40 Signaling Pathway	Myeloid Cell Homeostasis DNA Repair Nucleotide-excision Repair Germ Cell Development Removal Of Superoxide Radicals Cellular Response To Oxidative Stress Interstrand Cross-link Repair Brain Morphogenesis Protein-containing Complex Assembly Neuronal Stem Cell Population Maintenance
Pathways		Fanconi Anemia Pathway TP53 Regulates Transcription of DNA Repair Genes	Fanconi Anemia Pathway TP53 Regulates Transcription of DNA Repair Genes
Drugs
Diseases		Fanconi anemia	Fanconi anemia
GWAS		Alzheimer's disease ( 24755620) Waist-to-hip ratio adjusted for BMI ( 28552196)	Birth weight ( 31043758) Offspring birth weight ( 31043758) Polycystic ovary syndrome ( 26284813)
Interacting Genes		28 interacting genes: ATM ATR BLM BRCA1 BRCA2 BRIP1 FANCC FANCE FANCI FANCL H2AC4 H2BC3 H3C1 H4C1 MEN1 MRE11 NBN PCNA RAD51 TERF1 TNFRSF1A TNFRSF1B TNKS UBB UBE2T UHRF1 UHRF2 USP1	34 interacting genes: AZIN1 CAPN10 CCNA2 CDK1 CTBP1 DNAJB1 FANCA FANCD2 FANCE FANCF FANCG GSTP1 HSP90AA1 HSP90B1 HSPA1A HSPA4 HSPA8 IK KRT1 MEOX2 MT-ATP6 POR PRDX3 PRPF31 RPL18 RPS3A SPTA1 SPTAN1 STAT1 STMN1 STMN2 TCERG1 USP14 ZBTB32
Entrez ID		2177	2176
HPRD ID		01968	01967
Ensembl ID		ENSG00000144554	ENSG00000158169
Uniprot IDs		Q9BXW9	A0A024R9N2 A0A087WW44 B4E3W2 Q00597
PDB IDs
Enriched GO Terms of Interacting Partners?
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