EXTL1 and SDR16C5

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		EXTL1	SDR16C5
Description		exostosin like glycosyltransferase 1	short chain dehydrogenase/reductase family 16C member 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Golgi Apparatus Integral Component Of Membrane	Chromatin Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Plasma Membrane Integral Component Of Membrane Transcriptional Repressor Complex
	Molecular Function	Acetylglucosaminyltransferase Activity Glucuronosyltransferase Activity Transferase Activity, Transferring Glycosyl Groups Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase Activity	Transcription Corepressor Activity Retinol Dehydrogenase Activity Transcription Factor Binding Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Activating Transcription Factor Binding
	Biological Process	Skeletal System Development Protein Glycosylation IRE1-mediated Unfolded Protein Response	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Histone Deacetylation Negative Regulation Of Histone Acetylation Retinol Metabolic Process Retinal Metabolic Process Keratinocyte Proliferation Oxidation-reduction Process
Pathways		XBP1(S) activates chaperone genes	RA biosynthesis pathway
Drugs
Diseases
GWAS			Depressive symptoms x dependent stressful life events interaction (2df test) ( 30718454) Height ( 28552196 20881960 31562340)
Interacting Genes		1 interacting genes: SDR16C5	2 interacting genes: EXTL1 NLK
Entrez ID		2134	195814
HPRD ID		03441	12351
Ensembl ID		ENSG00000158008	ENSG00000170786
Uniprot IDs		Q92935	B3KT84 G3V145 Q8N3Y7
PDB IDs
Enriched GO Terms of Interacting Partners?
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