ETV5 and SLC22A2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		ETV5	SLC22A2
Description		ETS variant transcription factor 5	solute carrier family 22 member 2
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Plasma Membrane Synapse	Plasma Membrane Integral Component Of Plasma Membrane Membrane Extracellular Exosome Presynapse
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Regulatory Region DNA Binding	Organic Cation Transmembrane Transporter Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Neuromuscular Synaptic Transmission Locomotory Behavior Cell Differentiation Cellular Response To Oxidative Stress Positive Regulation Of Neuron Differentiation Positive Regulation Of Transcription By RNA Polymerase II Male Germ-line Stem Cell Asymmetric Division Regulation Of Synapse Organization Positive Regulation Of Glial Cell Proliferation Regulation Of Branching Involved In Mammary Gland Duct Morphogenesis Skeletal Muscle Acetylcholine-gated Channel Clustering	Drug Transmembrane Transport Neurotransmitter Secretion Body Fluid Secretion Organic Cation Transport Neurotransmitter Biosynthetic Process
Pathways			Neurotransmitter clearance Norepinephrine Neurotransmitter Release Cycle Abacavir transmembrane transport Na+/Cl- dependent neurotransmitter transporters Organic cation transport
Drugs
Diseases		Prostate cancer
GWAS		Bipolar disorder or body mass index ( 31754094) BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) BMI in smokers ( 28443625) Body mass index ( 28552196 23563607 19079260 26961502 28892062 25673413 20935630 28448500) Body mass index (adult) ( 28430825) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically active individuals ( 28448500) Body mass index in physically inactive individuals ( 28448500) Creatinine levels ( 29124443) Estimated glomerular filtration rate ( 31152163 31451708 29124443 30604766) Estimated glomerular filtration rate in non-diabetics ( 31451708) Glomerular filtration rate (creatinine) ( 28452372) Glomerular filtration rate in non diabetics (creatinine) ( 26831199) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) High density lipoprotein cholesterol levels ( 29083408) Hip circumference ( 25673412) Hyperuricemia ( 29124443) Menarche (age at onset) ( 27182965 21102462) Obesity ( 23563607) Serum uric acid levels ( 29124443) Waist circumference ( 25673412) Weight ( 19079260)	Body mass index ( 26426971 25673413) Body mass index (age>50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Chronic kidney disease ( 31152163 20383146) Creatinine levels ( 31015462 29403010 20383145) Estimated glomerular filtration rate ( 31152163 31015462 31451708 30604766) Estimated glomerular filtration rate in diabetes ( 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) Familial squamous cell lung carcinoma ( 29924316) Glomerular filtration rate ( 27588450 29403010) Glomerular filtration rate (creatinine) ( 28452372 26831199) Glomerular filtration rate in non diabetics (creatinine) ( 26831199) Kidney stones ( 31729369) Lipoprotein (a) levels ( 26377243) Lipoprotein (a) levels in coronary artery disease (percutaneous coronary intervention) ( 31186284) Prostate cancer ( 26034056) Serum metabolite levels ( 23093944) Waist circumference ( 26785701)
Interacting Genes		14 interacting genes: AMH AP2M1 APP AR BRCA1 CCR5 CISH CYP3A5 DHRS7 GRAP2 HOXD9 MFHAS1 SEZ6L2 SLC22A2	9 interacting genes: AGO3 CST9L ETV5 EXT2 GTF2B HYAL3 LSM4 POU2AF1 SUMO2
Entrez ID		2119	6582
HPRD ID		09035	04008
Ensembl ID		ENSG00000244405	ENSG00000112499
Uniprot IDs		P41161	O15244
PDB IDs		4UNO 5ILV
Enriched GO Terms of Interacting Partners?
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