SENP5 and SUMO3

Number of citations of the paper that reports this interaction (PubMedID 16608850)
85

Data Source:
BioGRID (enzymatic study)

		SENP5	SUMO3
Description		SUMO specific peptidase 5	small ubiquitin like modifier 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Plasma Membrane	Kinetochore Nucleus Nucleoplasm Cytoplasm PML Body
	Molecular Function	Protein Binding SUMO-specific Protease Activity Ubiquitin-like Protein-specific Protease Activity	Protein Binding Enzyme Binding
	Biological Process	Cell Cycle Protein Sumoylation Protein Desumoylation Cell Division	Protein Sumoylation Negative Regulation Of DNA Binding
Pathways		SUMO is proteolytically processed	SUMO is conjugated to E1 (UBA2:SAE1) SUMO is transferred from E1 to E2 (UBE2I, UBC9) SUMO is proteolytically processed SUMOylation of DNA damage response and repair proteins SUMOylation of transcription factors SUMOylation of transcription cofactors SUMOylation of intracellular receptors SUMOylation of intracellular receptors SUMOylation of chromatin organization proteins SUMOylation of DNA replication proteins SUMOylation of immune response proteins Formation of Incision Complex in GG-NER
Drugs
Diseases
GWAS		Gestational age at birth (child effect) ( 31194736) Night sleep phenotypes ( 27126917)	Delirium ( 29631748)
Interacting Genes		3 interacting genes: RABGAP1 SUMO2 SUMO3	47 interacting genes: ANXA7 BLM CCNE2 CDKN1A CEBPA CHAF1A CUL3 DAXX EGLN3 FOS HIPK2 HSF1 HSF2 JUN KALRN MAPKAPK3 PFDN1 PIAS1 PIAS2 PIAS3 PIAS4 PML RANGAP1 RNF111 RNF8 SAE1 SENP1 SENP2 SENP5 SMN1 SOX10 SOX6 SP100 TDG TDP2 TK1 TP53BP2 TTR UBA2 UBE2I UBE3A UPF2 USP25 USPL1 VIM WWTR1 YAP1
Entrez ID		205564	6612
HPRD ID		10222	03754
Ensembl ID		ENSG00000119231	ENSG00000184900
Uniprot IDs		B2R9F5 Q96HI0	P55854
PDB IDs			1U4A 2IO1 2MP2 6K5R 6NNQ
Enriched GO Terms of Interacting Partners?
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