EPAS1 and ARNTL

  • Number of citations of the paper that reports this interaction (PubMedID 9576906)
  • 208
  • Data Source:
  • HPRD (two hybrid, in vivo)

EPAS1

ARNTL

Description endothelial PAS domain protein 1 aryl hydrocarbon receptor nuclear translocator like
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Body mass index ( 25673413)
  • C-reactive protein levels ( 30388399)
  • C-reactive protein levels or triglyceride levels (pleiotropy) ( 27286809)
  • Chronic obstructive pulmonary disease ( 30804561)
  • Chronotype ( 30696823)
  • Coronary artery disease ( 29212778)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Diastolic blood pressure ( 27841878 27618448 30487518)
  • Diastolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Face memory ( 31596458)
  • Feeling guilty ( 29500382)
  • Feeling miserable ( 29500382)
  • General risk tolerance (MTAG) ( 30643258)
  • HDL cholesterol ( 30275531)
  • HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Iron status biomarkers (transferrin levels) ( 25352340)
  • Lipid traits (pleiotropy) (HIPO component 1) ( 30289880)
  • Mean arterial pressure ( 30487518)
  • Medication use (agents acting on the renin-angiotensin system) ( 31015401)
  • Menarche (age at onset) ( 27182965 21102462 25231870)
  • Metabolic syndrome ( 31589552)
  • Neurociticism ( 29500382)
  • PEG-asparaginase hypersensitivity without enzyme activity in childhood acute lymphoblastic leukaemia ( 30450575)
  • Plasminogen activator inhibitor type 1 levels (PAI-1) ( 22990020)
  • Psoriasis ( 30921485)
  • Schizophrenia ( 23358160)
  • Systolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Tea consumption ( 31046077)
  • Triglyceride levels ( 30698716)
  • Triglyceride levels in current drinkers ( 30698716)
  • Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Worry too long after an embarrassing experience ( 29500382)
  • Worry/vulnerability (special factor of neuroticism) ( 30867560)
Interacting Genes 39 interacting genes: APC ARNT ARNT2 ARNTL ARNTL2 BATF BATF2 BATF3 BBS1 BBS2 BBS4 DBP DDIT3 EGLN1 EGLN2 EGLN3 EIF3E EP300 ESR1 ETV4 EWSR1 F12 HSP90AA1 JUN KLHL20 KPNA1 KPNA3 KPNA5 KPNA6 KPNB1 MAX MEF2C NDN PRKD1 SMAD3 SPP1 STAT5A TERF2IP VHL 21 interacting genes: AHR BHLHE40 CLOCK CRY1 CSNK1E DELEC1 EP300 EPAS1 HIF1A HLF HSP90AA1 KAT2B NPAS2 NPAS4 PER3 RARA RHOA RHOU RXRA SIRT1 UBE2I
Entrez ID 2034 406
HPRD ID 06787 03973
Ensembl ID ENSG00000116016 ENSG00000133794
Uniprot IDs B3KW07 Q99814 A0A140VKD3 B2RCL8 O00327
PDB IDs 1P97 2A24 3F1N 3F1O 3F1P 3H7W 3H82 4GHI 4GS9 4PKY 4XT2 5KIZ 5TBM 5UFP 6BVB 6CZW 6D09 6D0B 6D0C 6I7R 4H10
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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