EHHADH and TPP2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		EHHADH	TPP2
Description		enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase	tripeptidyl peptidase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Peroxisome Peroxisomal Matrix Cytosol	Nucleoplasm Cytoplasm Cytosol Nuclear Body
	Molecular Function	3-hydroxyacyl-CoA Dehydrogenase Activity Dodecenoyl-CoA Delta-isomerase Activity Enoyl-CoA Hydratase Activity Protein Binding Long-chain-enoyl-CoA Hydratase Activity Enzyme Binding	Endopeptidase Activity Aminopeptidase Activity Serine-type Endopeptidase Activity Protein Binding Tripeptidyl-peptidase Activity Identical Protein Binding
	Biological Process	Internal Protein Amino Acid Acetylation Protein Targeting To Peroxisome Fatty Acid Beta-oxidation Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase	Protein Polyubiquitination Proteolysis
Pathways		Beta-oxidation of very long chain fatty acids Peroxisomal protein import Peroxisomal protein import	Antigen processing: Ubiquitination & Proteasome degradation
Drugs		NADH
Diseases
GWAS		Cognitive performance ( 19734545) Major depressive disorder ( 27519822 21042317)
Interacting Genes		27 interacting genes: ACTB ACTG1 BHLHE40 CAT CBS CCDC102B DES FUNDC1 KCTD6 KCTD9 KRTAP10-7 LZTS2 MID1 NECAB2 PNMA1 SCP2 SSNA1 SSX2IP TNIP1 TPP2 TRAF1 TRIM27 TRIM41 TRIM54 TRIM55 TRIM63 ZBTB9	4 interacting genes: EHHADH MTNR1A POLB PPP1R16A
Entrez ID		1962	7174
HPRD ID		06125	01834
Ensembl ID		ENSG00000113790	ENSG00000134900
Uniprot IDs		Q08426	P29144 Q5VZU9
PDB IDs
Enriched GO Terms of Interacting Partners?
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