ECH1 and PAFAH1B3

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ECH1	PAFAH1B3
Description		enoyl-CoA hydratase 1	platelet activating factor acetylhydrolase 1b catalytic subunit 3
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Peroxisome Peroxisomal Matrix Cytosol Membrane Extracellular Exosome	Cytoplasm Cytosol Membrane
	Molecular Function	Protein Binding Delta3,5-delta2,4-dienoyl-CoA Isomerase Activity	1-alkyl-2-acetylglycerophosphocholine Esterase Activity Protein Binding Identical Protein Binding Protein-containing Complex Binding Platelet-activating Factor Acetyltransferase Activity
	Biological Process	Protein Targeting To Peroxisome Fatty Acid Beta-oxidation	Lipid Metabolic Process Spermatogenesis Nervous System Development Brain Development Lipid Catabolic Process
Pathways		Peroxisomal protein import Peroxisomal protein import	COPI-independent Golgi-to-ER retrograde traffic
Drugs			(1R)-1,2,2-trimethylpropyl (R)-methylphosphinate
Diseases
GWAS		Blood protein levels ( 30072576) Logical memory (immediate recall) in mild cognitive impairment ( 29274321)
Interacting Genes		11 interacting genes: APP CSTF2 EEF1D EEF1G FAM9B HTT PAFAH1B3 SERPINB9 STAT3 TIMP1 TLR10	33 interacting genes: BRD7 CCDC90B CHMP7 COPS6 CRMP1 DDX24 ECH1 EEF1A1 ERG28 GAPDH GBP2 GDF9 HSPH1 IGSF21 LNX1 LRIF1 MED31 PAFAH1B1 PAFAH1B2 PLEKHM1 RBM48 SDCBP2 SETDB1 SUMO4 TERF1 TERF2IP TLE1 TP53 TUBB2A UNC119 XRCC6 ZBTB16 ZHX1
Entrez ID		1891	5050
HPRD ID		02825	04354
Ensembl ID		ENSG00000104823	ENSG00000079462
Uniprot IDs		A0A384MR44 Q13011	A0A024R0L6 Q15102
PDB IDs		2VRE
Enriched GO Terms of Interacting Partners?
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