TOR1A and LRRC7

Number of citations of the paper that reports this interaction (PubMedID 15767459)
87

Data Source:
HPRD (in vivo)

		TOR1A	LRRC7
Description		torsin family 1 member A	leucine rich repeat containing 7
Image			No pdb structure
GO Annotations	Cellular Component	Cell Nuclear Envelope Endoplasmic Reticulum Endoplasmic Reticulum Lumen Cytosol Cytoskeleton Synaptic Vesicle Membrane Cell Junction Secretory Granule Growth Cone Cytoplasmic Vesicle Membrane Nuclear Membrane Extrinsic Component Of Endoplasmic Reticulum Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome	Extracellular Region Nucleoplasm Centrosome Cytosol Plasma Membrane Cell-cell Junction Adherens Junction Ionotropic Glutamate Receptor Complex Postsynaptic Density Basolateral Plasma Membrane Cell Junction Specific Granule Lumen Neuron Projection Axon Initial Segment Synapse Postsynaptic Membrane Synaptic Membrane
	Molecular Function	Protein Binding ATP Binding Cytoskeletal Protein Binding ATPase Activity Kinesin Binding Identical Protein Binding Unfolded Protein Binding Misfolded Protein Binding	Protein Binding
	Biological Process	Protein Deneddylation Response To Oxidative Stress Organelle Organization Nuclear Envelope Organization Cell Adhesion Neuron Projection Development Protein Localization To Nucleus Wound Healing, Spreading Of Cells Intermediate Filament Cytoskeleton Organization Synaptic Vesicle Transport Chaperone Cofactor-dependent Protein Refolding Regulation Of Dopamine Uptake Involved In Synaptic Transmission Chaperone-mediated Protein Folding ER-associated Misfolded Protein Catabolic Process Nuclear Membrane Organization Chaperone-mediated Protein Transport Positive Regulation Of Synaptic Vesicle Endocytosis Regulation Of Protein Localization To Cell Surface	MAPK Cascade Embryo Development Positive Regulation Of Neuron Projection Development Receptor Clustering Neutrophil Degranulation Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Receptor Localization To Synapse Cell-cell Adhesion Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Neurotransmitter Receptor Transport Postsynaptic Membrane To Endosome Regulation Of NMDA Receptor Activity
Pathways		Cargo recognition for clathrin-mediated endocytosis
Drugs
Diseases		Primary torsion dystonia (PTD)
GWAS		Prostate cancer ( 29892016) Prostate cancer (advanced) ( 29892016) Prostate cancer (early onset) ( 29892016)	Adventurousness ( 30643258) Attention deficit hyperactivity disorder ( 21784300) Body mass index ( 24348519) Cognitive decline rate in late mild cognitive impairment ( 26252872) Hypertension risk in short sleep duration ( 22322875) Obesity-related traits ( 23251661) Orofacial clefts ( 22419666) Psoriasis ( 25939698) Type 2 diabetes ( 31049640)
Interacting Genes		9 interacting genes: ENPP2 KRTAP10-7 LMNA LRRC7 NOTCH1 PAEP SNCA TOR1AIP2 TOR1B	11 interacting genes: ACTN2 ACTN4 ADGRB1 CAMK2A CAMK2G CDH2 CNKSR2 CTNND2 HOMEZ NQO2 TOR1A
Entrez ID		1861	57554
HPRD ID		06897	09930
Ensembl ID		ENSG00000136827	ENSG00000033122
Uniprot IDs		B3KPA1 O14656	A0A075B6E9
PDB IDs		5J1S 5J1T 6OIF
Enriched GO Terms of Interacting Partners?
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