DPEP1 and KIFBP

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid, affinity chromatography technology)
HPRD (two hybrid)

		DPEP1	KIFBP
Description		dipeptidase 1	kinesin family binding protein
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleoplasm Plasma Membrane Apical Plasma Membrane Cell Junction Anchored Component Of Membrane Microvillus Membrane Apical Part Of Cell Extracellular Exosome	Mitochondrion Cytoskeleton
	Molecular Function	Protein Binding Metalloexopeptidase Activity Dipeptidyl-peptidase Activity Zinc Ion Binding GPI Anchor Binding Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process Metallodipeptidase Activity Modified Amino Acid Binding	Protein Binding Kinesin Binding
	Biological Process	Proteolysis Leukotriene Metabolic Process Glutathione Metabolic Process Xenobiotic Metabolic Process Apoptotic Process Antibiotic Metabolic Process Negative Regulation Of Cell Migration Cellular Response To Drug Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Homocysteine Metabolic Process Cellular Response To Calcium Ion Cellular Response To Nitric Oxide Cellular Lactam Catabolic Process	In Utero Embryonic Development Mitochondrial Transport Nervous System Development Cell Differentiation
Pathways		Synthesis of Leukotrienes (LT) and Eoxins (EX) Aflatoxin activation and detoxification LTC4-CYSLTR mediated IL4 production
Drugs		Cilastatin
Diseases			Goldberg-Shprintzen megacolon syndrome; Goldberg-Shprintzen syndrome (GOSHS) Polymicrogyria; Bilateral frontal polymicrogyria (BFP); Bilateral frontoparietal polymicrogyria (BFPP); Bilateral perisylvian polymicrogyria (BPP); Bilateral parasagittal parieto-occipital polymicrogyria (BPOP); Bilateral generalised polymicrogyria (BGP); Unilateral Polymicrogyria (ULP)
GWAS		Blood protein levels ( 30072576) Chronic kidney disease ( 29124443) Creatinine levels ( 29124443) Diastolic blood pressure ( 27841878 27618447 27618448) Estimated glomerular filtration rate ( 31451708 29124443 30604766) Glomerular filtration rate ( 27588450) Glomerular filtration rate (creatinine) ( 28452372) Glomerular filtration rate in non diabetics (creatinine) ( 26831199) Height ( 31562340) Homocysteine levels ( 23824729) Hypertension ( 27618447) Hyperuricemia ( 29124443) Red vs. brown/black hair color ( 30531825) Serum uric acid levels ( 29124443) Systolic blood pressure ( 27841878 27618447) Urinary albumin-to-creatinine ratio ( 31511532) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		2 interacting genes: APPBP2 KIFBP	11 interacting genes: ATXN2 CEP76 DOK2 DPEP1 EXOSC2 HBP1 PLEKHF1 RGR TERF1 ZNF638 ZNF670
Entrez ID		1800	26128
HPRD ID		01563	13848
Ensembl ID		ENSG00000015413	ENSG00000198954
Uniprot IDs		A0A140VJI3 P16444	Q96EK5
PDB IDs		1ITQ 1ITU
Enriched GO Terms of Interacting Partners?
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