DNM1 and CLIC4

Number of citations of the paper that reports this interaction (PubMedID 11563969)
29

Data Source:
HPRD (in vitro)

		DNM1	CLIC4
Description		dynamin 1	chloride intracellular channel 4
Image
GO Annotations	Cellular Component	Photoreceptor Inner Segment Nucleoplasm Cytoplasm Golgi Apparatus Microtubule Plasma Membrane Synaptic Vesicle Postsynaptic Density Microtubule Cytoskeleton Membrane Membrane Coat Axon Cytoplasmic Vesicle Mitochondrial Membrane Varicosity Dendritic Spine Dendritic Spine Head Synapse Postsynaptic Membrane Extracellular Exosome Photoreceptor Ribbon Synapse Presynaptic Endocytic Zone Membrane Postsynaptic Endocytic Zone Membrane Glutamatergic Synapse	Intracellular Cell Nucleus Cytoplasm Mitochondrion Centrosome Cytosol Plasma Membrane Microvillus Cell-cell Junction Cell Surface Actin Cytoskeleton Microtubule Cytoskeleton Nuclear Matrix Midbody Cytoplasmic Vesicle Membrane Chloride Channel Complex Apical Part Of Cell Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	RNA Binding GTPase Activity Protein Binding GTP Binding Microtubule Binding Protein C-terminus Binding SH3 Domain Binding Protein Kinase Binding D2 Dopamine Receptor Binding Identical Protein Binding Protein-containing Complex Binding Nitric-oxide Synthase Binding	Voltage-gated Ion Channel Activity Chloride Channel Activity Protein Binding
	Biological Process	Mitochondrial Fission G Protein-coupled Receptor Internalization Endocytosis Receptor-mediated Endocytosis Endosome Organization Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Receptor Internalization Ephrin Receptor Signaling Pathway Organelle Fission Regulation Of Synapse Structure Or Activity Modulation Of Chemical Synaptic Transmission Membrane Fusion Postsynaptic Neurotransmitter Receptor Internalization Positive Regulation Of Synaptic Vesicle Endocytosis Toxin Transport Response To Amyloid-beta	Angiogenesis Endothelial Cell Morphogenesis Chloride Transport Vacuolar Acidification Fertilization Cell Differentiation Keratinocyte Differentiation Negative Regulation Of Cell Migration Regulation Of Ion Transmembrane Transport Establishment Or Maintenance Of Apical/basal Cell Polarity Multicellular Organism Growth Branching Morphogenesis Of An Epithelial Tube Regulation Of Cytoskeleton Organization Retina Vasculature Morphogenesis In Camera-type Eye Cellular Response To Calcium Ion Chloride Transmembrane Transport
Pathways		Toll Like Receptor 4 (TLR4) Cascade Retrograde neurotrophin signalling Gap junction degradation Formation of annular gap junctions MHC class II antigen presentation EPH-ephrin mediated repulsion of cells Recycling pathway of L1 Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder ( 18839057) Body mass index ( 26426971) Coenzyme Q10 levels ( 27149984)	Heel bone mineral density ( 30598549) Height ( 20881960) Male-pattern baldness ( 28196072) Systolic blood pressure ( 29208002)
Interacting Genes		46 interacting genes: AMPH AP2A2 ASB13 BIN1 CABIN1 CAV1 CDK5 CEP126 CLIC3 CLIC4 CLINT1 CTTN DNM2 DNMBP EPS15 FNBP1 GRB2 GRIN1 GRIN2D ITSN1 MAP3K10 MED31 MOB4 NCK1 NCK2 NME2 PACSIN1 PACSIN2 PACSIN3 PFN2 PIAS1 PIK3R1 PIN4 PLCG1 PRKCA PRNP RACK1 SH3GL1 SH3GL2 SH3GL3 SNAP25 SNX9 SRC SUMO1 TIMM50 UBE2I	5 interacting genes: ACTB DNM1 HSP90AB1 REL YWHAZ
Entrez ID		1759	25932
HPRD ID		03851	05943
Ensembl ID		ENSG00000106976	ENSG00000169504
Uniprot IDs		B4DK06 B7ZAC0 Q05193	Q6FIC5 Q9Y696
PDB IDs		1DYN 2DYN 2X2E 2X2F 3SNH 3ZYC 3ZYS 4UUD 4UUK 5D3Q 6DLU 6DLV	2AHE 2D2Z 3OQS
Enriched GO Terms of Interacting Partners?
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