SEPTIN1 and TOLLIP

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
HPRD (two hybrid)

		SEPTIN1	TOLLIP
Description		septin 1	toll interacting protein
Image		No pdb structure
GO Annotations	Cellular Component	Microtubule Organizing Center Septin Ring Synaptic Vesicle Microtubule Cytoskeleton Midbody Septin Complex Cell Division Site	Extracellular Region Cytoplasm Cytosol Nuclear Body Azurophil Granule Lumen Specific Granule Lumen Interleukin-18 Receptor Complex Interleukin-1 Receptor Complex Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	GTPase Activity Protein Binding GTP Binding Identical Protein Binding Molecular Adaptor Activity	Interleukin-1, Type I Receptor Binding Protein Binding Kinase Binding Ubiquitin Conjugating Enzyme Binding Ubiquitin Protein Ligase Binding SUMO Binding Toll-like Receptor Binding Ubiquitin Binding
	Biological Process	Regulation Of Exocytosis Cellular Protein Localization Cytoskeleton-dependent Cytokinesis	Ubiquitin-dependent Protein Catabolic Process Autophagy Inflammatory Response Signal Transduction Cell-cell Signaling Phosphorylation Epithelial Cell Differentiation Positive Regulation Of Protein Sumoylation Intracellular Signal Transduction Protein Localization To Endosome Neutrophil Degranulation Innate Immune Response Leukocyte Activation Interleukin-1-mediated Signaling Pathway
Pathways			Neutrophil degranulation Interleukin-1 signaling
Drugs
Diseases
GWAS			Idiopathic pulmonary fibrosis ( 24429156)
Interacting Genes		10 interacting genes: AMOT APP AURKB SEPTIN12 SEPTIN5 SEPTIN6 SEPTIN9 TEX11 TOLLIP UBC	44 interacting genes: ACTN2 ATXN1 BHLHE40 CHD6 CPSF6 CSN1S1 CSN2 CSTF1 DAB1 DAZAP2 DZIP3 EIF2AK2 FTH1 GGA1 GGA2 GGA3 HERPUD1 IL1R1 IL1RAP IRAK1 IRAK2 LDB1 N4BP2 NTAQ1 ODAM PEG10 PRR20A RBFOX2 RBPMS RHOXF2 SEPTIN1 SETDB1 SIAH1 TBX3 TLR2 TLR4 TOM1 TOM1L1 UBC WBP2 WRNIP1 XRN2 ZBTB16 ZHX1
Entrez ID		1731	54472
HPRD ID		15324	05887
Ensembl ID		ENSG00000180096	ENSG00000078902
Uniprot IDs		J3KNL2 Q8WYJ6	B3KR28 E9PNS3 F2Z2Y8 Q6FIE9 Q8N8J5 Q9H0E2
PDB IDs			1WGL 2N31
Enriched GO Terms of Interacting Partners?
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