CYB5R3 and HBG2

Number of citations of the paper that reports this interaction (PubMedID 4403130)
22

Data Source:
HPRD (in vitro)

		CYB5R3	HBG2
Description		cytochrome b5 reductase 3	hemoglobin subunit gamma 2
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GO Annotations	Cellular Component	Extracellular Region Cytoplasm Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Hemoglobin Complex Membrane Azurophil Granule Lumen	Cytosol Hemoglobin Complex Haptoglobin-hemoglobin Complex Blood Microparticle
	Molecular Function	Cytochrome-b5 Reductase Activity, Acting On NAD(P)H Protein Binding AMP Binding ADP Binding NAD Binding FAD Binding	Peroxidase Activity Oxygen Carrier Activity Oxygen Binding Heme Binding Haptoglobin Binding Hemoglobin Alpha Binding Organic Acid Binding Metal Ion Binding
	Biological Process	Cholesterol Biosynthetic Process Xenobiotic Metabolic Process Blood Circulation L-ascorbic Acid Metabolic Process Neutrophil Degranulation Oxidation-reduction Process	Blood Coagulation Oxygen Transport Hydrogen Peroxide Catabolic Process Cellular Oxidant Detoxification
Pathways		Vitamin C (ascorbate) metabolism Phase I - Functionalization of compounds Neutrophil degranulation	Factors involved in megakaryocyte development and platelet production
Drugs		NADH Flavin adenine dinucleotide Copper
Diseases		Methemoglobinemia
GWAS		Initial pursuit acceleration ( 29064472)	Beta thalassemia/hemoglobin E disease ( 20183929) Hemoglobin ( 28548082) Hemoglobin levels ( 26366553) Logical memory (delayed recall) in normal cognition ( 29274321) Logical memory (immediate recall) in normal cognition ( 29274321) Malate levels ( 31560688) Mean corpuscular hemoglobin concentration ( 28453575) Red cell distribution width ( 27863252)
Interacting Genes		11 interacting genes: ARSA CYB5A CYCS GAS1 HBG2 L3MBTL2 RPS6KB1 SBF1 SPP1 TUBGCP6 XPNPEP3	5 interacting genes: APP CYB5R3 HBB RPSA SMAD5
Entrez ID		1727	3048
HPRD ID		08942	00792
Ensembl ID		ENSG00000100243	ENSG00000196565
Uniprot IDs		P00387	D9YZU9 P69892
PDB IDs		1M91 1UMK	1FDH 4MQJ 4MQK
Enriched GO Terms of Interacting Partners?
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