DDX10 and BCO2

		DDX10	BCO2
Description		DEAD-box helicase 10	beta-carotene oxygenase 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus	Mitochondrion Mitochondrial Matrix
	Molecular Function	RNA Binding RNA Helicase Activity ATP Binding	Beta-carotene 15,15'-monooxygenase Activity Retinal Isomerase Activity Carotenoid Dioxygenase Activity Oxidoreductase Activity, Acting On Single Donors With Incorporation Of Molecular Oxygen, Incorporation Of Two Atoms Of Oxygen Metal Ion Binding Beta,beta-carotene-9',10'-cleaving Oxygenase Activity
	Biological Process	RRNA Processing Anterior Head Development	Retinoid Metabolic Process Carotenoid Metabolic Process Carotene Metabolic Process Carotene Catabolic Process Xanthophyll Metabolic Process Retinoic Acid Metabolic Process Retinal Metabolic Process Regulation Of Mitochondrial Membrane Potential Oxidation-reduction Process Regulation Of Reactive Oxygen Species Metabolic Process
Pathways			Retinoid metabolism and transport
Drugs
Diseases
GWAS		Knee osteoarthritis ( 28916551) Systolic blood pressure ( 27841878)	Immune reponse to smallpox (secreted IL-12p40) ( 22610502) Inflammatory biomarkers ( 24182552) Interleukin-18 levels ( 20150558 31584380)
Interacting Genes		16 interacting genes: ANTXR2 APP ARHGAP20 ARL2BP BCO2 CUL5 DES DSC3 FBXO7 HSPB2 IGFBP6 NPAT PGR PTS SIRPA SLN	1 interacting genes: DDX10
Entrez ID		1662	83875
HPRD ID		03138	12522
Ensembl ID		ENSG00000178105	ENSG00000197580
Uniprot IDs		Q13206	B2RCV8 Q9BYV7
PDB IDs		2PL3
Enriched GO Terms of Interacting Partners?
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