AP2B1 and MLH1

  • Number of citations of the paper that reports this interaction (PubMedID 16189514)
  • 1016
  • Data Source:
  • HPRD (two hybrid)

AP2B1

MLH1

Description adaptor related protein complex 2 subunit beta 1 mutL homolog 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Cerebrospinal AB1-42 levels in normal cognition ( 29274321)
  • Chronotype ( 30696823)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • High light scatter reticulocyte count ( 27863252)
  • High light scatter reticulocyte percentage of red cells ( 27863252)
  • Mean platelet volume ( 22139419 27863252)
  • Platelet count ( 22139419 27863252)
  • Platelet distribution width ( 27863252)
  • Reticulocyte count ( 27863252)
  • Reticulocyte fraction of red cells ( 27863252)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Schizophrenia ( 28991256)
  • Subjective response to lithium treatment ( 26503763)
Interacting Genes 48 interacting genes: ACVR1 AFF4 AP1M1 AP1M2 AP2A2 AP2M1 AP2S1 APC ARRB1 ATM ATP23 ATP6V1G1 BUB1 BUB1B CLINT1 DHX58 DNAJC5 EGFR GTF2I HIP1 HSPB1 ITSN1 KIAA0408 KPNA2 LDLRAP1 MEA1 MLH1 NECAP2 NEU4 NUP54 PIP5K1C POM121 RAPGEF3 RIBC2 SLC25A6 SLC2A8 SMAD4 SMURF1 SNAP91 TENT5C TERF2IP TGFBR1 TGFBR2 THAP1 TUBGCP4 TXN2 U2AF1 UBC 84 interacting genes: ABCC3 ABHD16A ACER3 ACTG2 AGR2 AIFM1 ALDOA ANXA6 AP2B1 APRT ARAF ASS1 ATF2 BLM BRCA1 CAB39L CAPN5 CASP3 CBY2 CCDC33 CDCA7L CEP126 CEP76 CKAP4 CKB DDX47 EEF1G EEF2 EIF2A ELP6 EXO1 EXOC3 FBXO32 FCGBP FLNB FRMD6 GABARAP GPX1 GSTP1 IGKC KPNA2 LGALS4 LY96 MAGEA8 MAP2K6 MBD4 MLH3 MSH3 MSH4 MUC2 MYC MYL6 MYOG NDRG1 NT5C3B ORC4 PARP12 PARVA PCNA PMS1 PMS2 PSMA1 PTGDS PTPRH RAD23B RAD9A RADX RAPGEFL1 SEC61A1 SELENBP1 SERPINF1 SQSTM1 STAP2 TASOR2 TLE5 TRIM23 TRIM29 TXN TXN2 UBOX5 VAMP8 ZBED1 ZC3H11A ZER1
Entrez ID 163 4292
HPRD ID 03015 00390
Ensembl ID ENSG00000006125 ENSG00000076242
Uniprot IDs A0A140VJE8 P63010 Q96EL6 A0A024R2S9 P40692 Q59EG3
PDB IDs 1E42 2G30 2IV8 2IV9 2JKR 2JKT 2VGL 2XA7 4UQI 5M5R 6QH5 6QH6 6QH7 3RBN 4P7A 5U5P
Enriched GO Terms of Interacting Partners?
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