CUX1 and SDC3

Number of citations of the paper that reports this interaction (PubMedID 8662884)
5

Data Source:
HPRD (in vitro)

		CUX1	SDC3
Description		cut like homeobox 1	syndecan 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleus Nucleoplasm Golgi Apparatus Cytosol	Golgi Lumen Plasma Membrane Cell Surface Membrane Integral Component Of Membrane Lysosomal Lumen Microspike Collagen-containing Extracellular Matrix
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding Protein Binding, Bridging Sequence-specific DNA Binding	Protein Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Retrograde Transport, Vesicle Recycling Within Golgi Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Golgi Vesicle Transport Positive Regulation Of Dendrite Morphogenesis	Retinoid Metabolic Process Glycosaminoglycan Biosynthetic Process Glycosaminoglycan Catabolic Process Cell Migration Leukocyte Migration
Pathways		Signaling by cytosolic FGFR1 fusion mutants Signaling by FGFR1 in disease Intra-Golgi traffic	A tetrasaccharide linker sequence is required for GAG synthesis HS-GAG biosynthesis HS-GAG biosynthesis HS-GAG degradation Cell surface interactions at the vascular wall Syndecan interactions Syndecan interactions Defective B4GALT7 causes EDS, progeroid type Defective B3GAT3 causes JDSSDHD Defective EXT2 causes exostoses 2 Defective EXT1 causes exostoses 1, TRPS2 and CHDS Defective B3GALT6 causes EDSP2 and SEMDJL1 Retinoid metabolism and transport
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder symptom score ( 27663945) Basal cell carcinoma ( 31174203 27539887) Breast cancer ( 29059683) Cerebellum cortex volume ( 31530798) Chronotype ( 30696823) Intelligence (MTAG) ( 29326435) Keratinocyte cancer (MTAG) ( 31174203) Mean platelet volume ( 27863252) Morning person ( 30696823) Platelet distribution width ( 27863252) Plateletcrit ( 27863252) Response to antidepressants ( 22584459) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)	Loneliness ( 27629369)
Interacting Genes		21 interacting genes: BIN1 CA12 CCNA1 CDC25A CDK1 CDK7 CREBBP CTSL CYTH2 EHMT2 ELAC2 GOLGA5 HMGB1 KAT2B MAX RB1 RECQL5 SATB1 SDC3 SUMO2 TLE4	18 interacting genes: CASK COL5A1 CSK CTTN CUX1 EPHB4 FGF2 FYN ITGB4 KRTAP10-3 KRTAP2-4 KRTAP4-2 KRTAP5-9 MDK PTN TUBA1A TUBB TUBB2A
Entrez ID		1523	9672
HPRD ID		00295	01719
Ensembl ID		ENSG00000257923	ENSG00000162512
Uniprot IDs		P39880 Q13948 Q3LIA3	O75056
PDB IDs
Enriched GO Terms of Interacting Partners?
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