CSTF2 and CSTF3

Number of citations of the paper that reports this interaction (PubMedID 22939629)
262

Data Source:
BioGRID (biochemical, pull down, affinity chromatography technology, biochemical)
HPRD (in vitro)

		CSTF2	CSTF3
Description		cleavage stimulation factor subunit 2	cleavage stimulation factor subunit 3
Image
GO Annotations	Cellular Component	Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex Nuclear Body Cleavage Body	Nucleus Nucleoplasm
	Molecular Function	RNA Binding MRNA Binding Protein Binding	RNA Binding MRNA Binding Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription MRNA Polyadenylation TRNA Splicing, Via Endonucleolytic Cleavage And Ligation MRNA 3'-end Processing Pre-mRNA Cleavage Required For Polyadenylation	MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription MRNA Polyadenylation MRNA Cleavage RNA 3'-end Processing MRNA 3'-end Processing
Pathways		tRNA processing in the nucleus mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs	mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS			Anger ( 24489884) Non-response to citalopram or escitalopram and depression ( 27622933)
Interacting Genes		23 interacting genes: APP BAG6 CEP126 CHD3 CSTF3 DDX1 ECH1 EEF1G ELP1 ERG28 FEZ1 HGS IMMT KAT5 POLR2A SPAG8 SS18L1 SUB1 SYMPK TFG UBQLN1 UBQLN4 ZNF341	3 interacting genes: CPSF1 CSTF1 CSTF2
Entrez ID		1478	1479
HPRD ID		02652	02651
Ensembl ID		ENSG00000101811	ENSG00000176102
Uniprot IDs		B3V096 B4DUD5 E7EWR4 P33240	Q12996
PDB IDs		1P1T 2J8P	6B3X 6URO
Enriched GO Terms of Interacting Partners?
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