CSNK1D and PER2

Number of citations of the paper that reports this interaction (PubMedID 15800623)
237

Data Source:
BioGRID (two hybrid)
HPRD (in vitro)

		CSNK1D	PER2
Description		casein kinase 1 delta	period circadian regulator 2
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Centrosome Spindle Cytosol Spindle Microtubule Plasma Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Perinuclear Region Of Cytoplasm	Nucleus Nucleolus Cytoplasm Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Cadherin Binding Tau-protein Kinase Activity	Transcription Regulatory Region Sequence-specific DNA Binding Transcription Corepressor Binding Transcription Coactivator Activity Protein Binding Transcription Factor Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Protein Phosphorylation Protein Phosphorylation Microtubule Nucleation Golgi Organization Regulation Of G2/M Transition Of Mitotic Cell Cycle Wnt Signaling Pathway Peptidyl-serine Phosphorylation Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Circadian Regulation Of Gene Expression Protein Localization To Golgi Apparatus Regulation Of Circadian Rhythm COPII Vesicle Coating Spindle Assembly Protein Localization To Cilium Protein Localization To Centrosome Positive Regulation Of Canonical Wnt Signaling Pathway Ciliary Basal Body-plasma Membrane Docking Positive Regulation Of Wnt-mediated Midbrain Dopaminergic Neuron Differentiation Non-motile Cilium Assembly Positive Regulation Of Non-canonical Wnt Signaling Pathway	Negative Regulation Of Transcription By RNA Polymerase II Response To Ischemia Glycogen Biosynthetic Process Gluconeogenesis Fatty Acid Metabolic Process Circadian Rhythm Response To Light Stimulus Regulation Of Vasoconstriction Lactate Biosynthetic Process Negative Regulation Of Protein Ubiquitination Circadian Regulation Of Gene Expression Regulation Of Circadian Rhythm Negative Regulation Of Circadian Rhythm Entrainment Of Circadian Clock By Photoperiod Negative Regulation Of Transcription, DNA-templated Regulation Of Neurogenesis Regulation Of Insulin Secretion White Fat Cell Differentiation Regulation Of Cell Cycle Regulation Of Glutamate Uptake Involved In Transmission Of Nerve Impulse Negative Regulation Of Fat Cell Proliferation Histone H3 Deacetylation Circadian Regulation Of Translation Positive Regulation Of Cold-induced Thermogenesis Positive Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Transcription Regulatory Region DNA Binding
Pathways		COPII-mediated vesicle transport Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Circadian Clock Anchoring of the basal body to the plasma membrane Major pathway of rRNA processing in the nucleolus and cytosol AURKA Activation by TPX2	Circadian Clock
Drugs
Diseases			Familial advanced sleep phase syndrome
GWAS			Chronotype ( 26955885 30696823 27494321) Morning vs. evening chronotype ( 26955885 26835600 27494321)
Interacting Genes		32 interacting genes: AKAP9 APP ARFGAP1 ATM BACE1 BRCA1 CDK5 CTNNB1 DVL1 DVL3 GJA1 HIF1A JPT2 KDR LURAP1 MAPT PER1 PER2 PER3 PPP1R14A PPP5C PSEN2 PTPRD RAB1A SMAD2 SMAD3 SMURF1 SNAPIN SNCA TP53 TRIM9 YWHAZ	19 interacting genes: BHLHE41 BTRC CLOCK CRY1 CRY2 CSNK1D CSNK1E CSNK2B DELEC1 MDM2 PER1 PER3 RORC TIMELESS TP53 TPT1 UBE2D1 UBE2D2 UBE2D3
Entrez ID		1453	8864
HPRD ID		02920	04575
Ensembl ID		ENSG00000141551	ENSG00000132326
Uniprot IDs		P48730	O15055
PDB IDs		3UYS 3UYT 3UZP 4HGT 4HNF 4KB8 4KBA 4KBC 4KBK 4TN6 4TW9 4TWC 5IH4 5IH5 5IH6 5MQV 5OKT 5W4W 6F1W 6F26 6GZM 6HMP 6HMR
Enriched GO Terms of Interacting Partners?
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