CRYAB and APOC2

  • Number of citations of the paper that reports this interaction (PubMedID 23159935)
  • 10

CRYAB

APOC2

Description crystallin alpha B apolipoprotein C2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease (onset between ages 58 and 79) ( 30979435)
  • Alzheimer's disease or HDL levels (pleiotropy) ( 30805717)
  • Blood protein levels ( 28240269)
  • Carotid intima media thickness (maximum) ( 31801372)
  • Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321)
  • Cerebrospinal AB1-42 levels in mild cognitive impairment ( 29274321)
  • Cerebrospinal AB1-42 levels in normal cognition ( 29274321)
  • Cerebrospinal fluid AB1-42 levels ( 29274321)
  • Cerebrospinal fluid p-tau levels ( 29274321)
  • Cerebrospinal fluid p-tau levels in mild cognitive impairment ( 29274321)
  • Cerebrospinal fluid t-tau levels ( 29274321)
  • Cerebrospinal fluid t-tau levels in mild cognitive impairment ( 29274321)
  • Cholesterol, total ( 20686565)
  • HDL cholesterol ( 20686565)
  • HDL cholesterol levels ( 28334899)
  • Hippocampal volume ( 29274321)
  • Hippocampal volume in Alzheimer's disease dementia ( 29274321)
  • LDL cholesterol ( 18802019 18193044 20864672 19060906 20686565)
  • LDL cholesterol levels ( 28334899)
  • Lipid metabolism phenotypes ( 22286219)
  • Logical memory (delayed recall) ( 29274321)
  • Logical memory (immediate recall) ( 29274321)
  • Low density lipoprotein cholesterol levels ( 28548082)
  • Quantitative traits ( 19197348)
  • Total cholesterol levels ( 28334899 28548082)
  • Triglyceride levels ( 28334899)
  • Triglycerides ( 20686565)
  • Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659)
Interacting Genes 49 interacting genes: ACOT7 APOC2 APP AVP B2M BAG3 BCL2L1 BMPR2 CASP3 CCL22 CCND1 CRYAA CRYBA1 CRYBB2 CRYGC CRYGD CRYGS CS DDX20 DES EPB41 FCGR2A FGF2 GFAP HBA1 HSPB1 HSPB2 HSPB6 HSPB8 INS KRTAP19-5 KRTAP8-1 LALBA MDH2 MIP MRPL11 NGF PRKAG3 PRNP PSMA3 SCN5A SNCA SOD1 SQSTM1 TNPO2 TRAPPC6A TTN UBE2D1 VEGFA 2 interacting genes: CRYAB LPL
Entrez ID 1410 344
HPRD ID 00428 07457
Ensembl ID ENSG00000109846 ENSG00000234906
Uniprot IDs A0A024R3B9 P02511 V9HW27 A0A024R0T9 P02655
PDB IDs 2KLR 2N0K 2WJ7 2Y1Y 2Y1Z 2Y22 2YGD 3J07 3L1G 3SGM 3SGN 3SGO 3SGP 3SGR 3SGS 4M5S 4M5T 5VVV 6BP9 1BY6 1I5J 1O8T 1SOH
Enriched GO Terms of Interacting Partners?
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