TCP10L and PMF1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		TCP10L	PMF1
Description		t-complex 10 like	polyamine modulated factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Centriole	MIS12/MIND Type Complex Condensed Chromosome Kinetochore Nuclear MIS12/MIND Complex Nucleoplasm Transcription Factor Complex Golgi Apparatus Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Transcription Corepressor Activity Protein Binding Identical Protein Binding Protein Self-association Repressing Transcription Factor Binding	Transcription Coactivator Activity Protein Binding Leucine Zipper Domain Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II	Transcription By RNA Polymerase II Cell Cycle Chromosome Segregation Cell Division Positive Regulation Of Nucleic Acid-templated Transcription
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS			Estimated glomerular filtration rate ( 30604766) Intracerebral hemorrhage ( 24656865) Ischemic stroke ( 29531354) Ischemic stroke (small-vessel) ( 29531354) Longevity (age >99th survival percentile) ( 31413261) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444 31624269) Non-lobar intracerebral hemorrhage (MTAG) ( 31430377) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Stroke ( 29531354) White matter hyperintensity burden ( 25663218)
Interacting Genes		9 interacting genes: APP DAPK3 FBXO25 IKBKG LRRK2 MXD4 PMF1 TNNC1 TNS2	17 interacting genes: CEP126 COPS6 COPS7A COPS7B CRMP1 DSN1 GDF9 GIT1 HSP90AA1 KDM1A MED31 MIS12 NFE2L2 PTN SUGT1 TCP10L USHBP1
Entrez ID		140290	11243
HPRD ID		10518	11441
Ensembl ID		ENSG00000242220	ENSG00000160783
Uniprot IDs		Q8TDR4	Q6P1K2
PDB IDs			5LSJ 5LSK
Enriched GO Terms of Interacting Partners?
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