CPT1A and KBTBD7

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		CPT1A	KBTBD7
Description		carnitine palmitoyltransferase 1A	kelch repeat and BTB domain containing 7
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Membrane Integral Component Of Mitochondrial Outer Membrane	Cellular_component Cytosol
	Molecular Function	Carnitine O-palmitoyltransferase Activity Identical Protein Binding Palmitoleoyltransferase Activity	Molecular_function Protein Binding
	Biological Process	Long-chain Fatty Acid Metabolic Process Glucose Metabolic Process Fatty Acid Metabolic Process Fatty Acid Beta-oxidation Triglyceride Metabolic Process Carnitine Shuttle Circadian Rhythm Carnitine Metabolic Process Response To Organic Cyclic Compound Regulation Of Lipid Metabolic Process Epithelial Cell Differentiation Positive Regulation Of Fatty Acid Beta-oxidation Response To Drug Eating Behavior Regulation Of Insulin Secretion Cellular Response To Fatty Acid	MAPK Cascade Biological_process Post-translational Protein Modification
Pathways		RORA activates gene expression PPARA activates gene expression Carnitine metabolism Signaling by Retinoic Acid	Regulation of RAS by GAPs Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs		L-Carnitine Glyburide Perhexiline
Diseases		Disorders of fatty-acid oxidation, including: Medium-chain (MC) acyl-CoA dehydrogenase (AD) deficiency (MCADD); Short-chain AD deficiency (SCADD) ; Short-branched-chain AD deficiency (SBCADD) ; Very long-chain AD deficiency (VLCADD) ; Long-chain 3-hydroxyacyl CoA dehydrogenase deficiency (LCHADD) ; Trifunctional protein deficiency (TFP); Carnitine palmitoyltransferase deficiency (CPT); Carnitine-acylcarnitine translocase deficiency (CACT); Systemic primary carnitine deficiency (CDSP)
GWAS		Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) Lipid metabolism phenotypes ( 22286219) Lipid traits (pleiotropy) (HIPO component 1) ( 30289880) Obesity-related traits ( 23251661) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271) Urate levels ( 31578528)
Interacting Genes		8 interacting genes: BCL2 CLIC1 CYBA HSPA5 KBTBD7 NPDC1 NR4A1 UBC	14 interacting genes: BARD1 BLMH C8orf33 CPT1A DUSP23 GABARAP GABARAPL1 GABARAPL2 HAP1 LRIF1 MAP1LC3B MAP1LC3C NFKBIE PHC2
Entrez ID		1374	84078
HPRD ID		02755	13759
Ensembl ID		ENSG00000110090	ENSG00000120696
Uniprot IDs		A0A024R5F4 B2RAQ8 P50416 Q8WZ48	Q8WVZ9
PDB IDs		2LE3
Enriched GO Terms of Interacting Partners?
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