CPEB2 and GAA

Number of citations of the paper that reports this interaction (PubMedID 22157746)
30

Data Source:
BioGRID (two hybrid)

		CPEB2	GAA
Description		cytoplasmic polyadenylation element binding protein 2	glucosidase alpha, acid
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Neuron Projection Synapse Messenger Ribonucleoprotein Complex	Cell Lysosome Lysosomal Membrane Plasma Membrane Membrane Azurophil Granule Membrane Lysosomal Lumen Extracellular Exosome Tertiary Granule Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	Translation Repressor Activity, MRNA Regulatory Element Binding RNA Binding MRNA 3'-UTR Binding GTPase Inhibitor Activity Translation Factor Activity, RNA Binding MRNA 3'-UTR AU-rich Region Binding Ribosome Binding Ribosomal Large Subunit Binding Ribosomal Small Subunit Binding	Alpha-1,4-glucosidase Activity Carbohydrate Binding Maltose Alpha-glucosidase Activity
	Biological Process	Translation Cellular Response To Insulin Stimulus Negative Regulation Of GTPase Activity Cellular Response To Oxidative Stress Cellular Response To Arsenic-containing Substance Cellular Response To Hypoxia Negative Regulation Of Cytoplasmic Translational Elongation Negative Regulation Of Cytoplasmic Translation	Maltose Metabolic Process Regulation Of The Force Of Heart Contraction Diaphragm Contraction Heart Morphogenesis Glycogen Catabolic Process Sucrose Metabolic Process Glucose Metabolic Process Lysosome Organization Locomotory Behavior Tissue Development Vacuolar Sequestering Neutrophil Degranulation Muscle Cell Cellular Homeostasis Neuromuscular Process Controlling Posture Neuromuscular Process Controlling Balance Cardiac Muscle Contraction
Pathways			Glycogen storage disease type II (GAA) Neutrophil degranulation Glycogen breakdown (glycogenolysis)
Drugs			Acarbose Miglitol AT2220
Diseases			Glycogen storage diseases (GSD), including: von Gierke disease (GSD type Ia); Pompe disease (GSD type II); Cori disease, Forbe disease (GSD type III); Andersen disease (GSD type IV); McArdle disease (GSD type V); Hers disease (GSD type VI); Tarui disease (GSD type VII); Phosphorylase kinase deficiency (GSD type IX); Fanconi-Bickel syndrome (GSD type XI); Glycogen synthase deficiency (GSD type 0)
GWAS		Cognitive flexibility ( 30134085)	Blood protein levels ( 30072576)
Interacting Genes		21 interacting genes: ATG2A ATP1B2 BSCL2 C2CD2L CAPN15 COPS7A ERI3 GAA GABBR1 GPX7 KEAP1 MT-ATP6 NECAB2 OTUB1 PIGS PSAP PUF60 SEMA4B SORBS3 SPARC TUBA1A	9 interacting genes: CPEB2 DYNC1LI2 EP300 HIVEP1 NCF1 NUMBL PARD3B SH3GLB2 STAT2
Entrez ID		132864	2548
HPRD ID		16744	06006
Ensembl ID		ENSG00000137449	ENSG00000171298
Uniprot IDs		Q7Z5Q1	P10253
PDB IDs			5KZW 5KZX 5NN3 5NN4 5NN5 5NN6 5NN8
Enriched GO Terms of Interacting Partners?
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