KLF6 and APOM

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KLF6	APOM
Description		Kruppel like factor 6	apolipoprotein M
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Fibrillar Center Nucleus Nucleoplasm Nucleolus Cytosol Intracellular Membrane-bounded Organelle	Extracellular Region Very-low-density Lipoprotein Particle Low-density Lipoprotein Particle High-density Lipoprotein Particle Discoidal High-density Lipoprotein Particle Spherical High-density Lipoprotein Particle
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding	Lipid Transporter Activity Phospholipid Binding Antioxidant Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II B Cell Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Retinoid Metabolic Process Response To Glucose Cholesterol Efflux High-density Lipoprotein Particle Remodeling High-density Lipoprotein Particle Assembly High-density Lipoprotein Particle Clearance Negative Regulation Of Plasma Lipoprotein Oxidation Lipoprotein Metabolic Process Cholesterol Homeostasis Reverse Cholesterol Transport Cellular Oxidant Detoxification
Pathways			Retinoid metabolism and transport
Drugs
Diseases
GWAS		Asthma (bronchodilator response) ( 23508266) Coronary artery calcification ( 23870195) Diastolic blood pressure ( 27841878) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) Heel bone mineral density ( 30598549 28869591) Multiple sclerosis ( 31604244) Plasma anti-thyroglobulin levels ( 29678681)	Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 30072576 29875488) Inflammatory bowel disease ( 28067908) Lung adenocarcinoma ( 19836008) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Rheumatoid arthritis ( 21844665) Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848) Squamous cell lung carcinoma ( 28604730) Ulcerative colitis ( 28067908)
Interacting Genes		16 interacting genes: APOM APP CELSR2 EHMT2 FBL GTF3C1 HDAC3 KLF4 LCOR NOP56 NUFIP1 PNO1 POLA2 SP1 TAF9 TP53	2 interacting genes: HGH1 KLF6
Entrez ID		1316	55937
HPRD ID		03632	06068
Ensembl ID		ENSG00000067082	ENSG00000204444
Uniprot IDs		D3GC14 Q99612	A0A1U9X793 O95445
PDB IDs			2WEW 2WEX 2YG2
Enriched GO Terms of Interacting Partners?
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