CLK2 and MRPL4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CLK2	MRPL4
Description		CDC like kinase 2	mitochondrial ribosomal protein L4
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Body Nuclear Speck	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Large Ribosomal Subunit
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding Identical Protein Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding
	Biological Process	Protein Phosphorylation Response To Ionizing Radiation Peptidyl-tyrosine Phosphorylation Response To Retinoic Acid Regulation Of RNA Splicing Negative Regulation Of Gluconeogenesis Protein Autophosphorylation	Mitochondrial Translational Elongation Mitochondrial Translational Termination
Pathways			Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination
Drugs
Diseases
GWAS		Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908)	Alanine transaminase levels ( 29403010) Pulse pressure ( 27841878) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		28 interacting genes: AKT1 CLK3 CPSF7 ECE1 GMCL1 KLHL2 LNX1 LUZP4 MRPL4 PRPF38A PTPN1 RBM39 RNPS1 RSRP1 SDCBP SRPK2 SRRM1 TRIM27 U2AF1 UBE2I UBL5 YTHDC1 YWHAG ZNF263 ZNF394 ZNF398 ZNF473 ZRSR2	9 interacting genes: CLK2 CSNK2A1 DDX24 ECSIT EIF2B1 EXOSC6 KRTAP4-12 TRIM23 XRN2
Entrez ID		1196	51073
HPRD ID		04289	14759
Ensembl ID		ENSG00000176444	ENSG00000105364
Uniprot IDs		A8K7I0 B7Z8N6 P49760	A0A024R7C5 Q9BYD3 X6RAY8
PDB IDs		3NR9 5UNP 6FYI 6FYK 6FYL 6KHE	3J7Y 3J9M 5OOL 5OOM 6NU2 6NU3
Enriched GO Terms of Interacting Partners?
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